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Altered ventricular dimensions and function in 6-month-old wild-type and Irx4Δex2/Δex2 mice. M-mode echocardiography shows increased LV wall thickness (LVWT) and LV end-systolic diameter (LVESD) but normal LV end-diastolic diameter (LVEDD) in Irx4Δex2/Δex2 mice (right) compared to those for wild-type animals (left).
