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. 2021 Dec 1;12:775659. doi: 10.3389/fimmu.2021.775659

Figure 4.

Figure 4

Complement-fixing activity of rabbit anti-CSP IgG to different regions of CSP. Rabbit anti-CSP IgG was tested for (A) IgG at 0.001-10 μg/ml and (B) C1q-fixation at 0.1-1000 μg/ml to CSP and antigens representing the N-terminal (NT), central-repeat (NANP) and C-terminal (CT) regions of CSP; x-axis was presented on a log10 scale. (C) The rabbit anti-CSP IgG was also tested at 100 μg/ml for C1q-fixation to CSP after pre-incubation with competing anitgen (including a no competition control); see Figure S1B for related data. Results were corrected for background reactivity using no-IgG control wells and the mean and range of two independent experiments is shown.