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. 2021 Nov 26;24(12):103520. doi: 10.1016/j.isci.2021.103520

Figure 6.

Figure 6

Proposed mechanism of action. Immature DCs phagocyte normal ACs, overexpressing P2X7

Once incorporated, ACs and DCs membrane fusion is induced (shown in red square), transferring cytoplasmic antigen from ACs to DCs. In addition, membrane transfer induces antigen-loaded MHC transfer, triggering antigen-specific T cell proliferation