Table 2.

Pooled estimated results for different types of mortality outcome

Mortality outcome type	Number of studies	Number of CRE patients	Number of CSE patients	Unweighted means of mortality among CRE patients	Unweighted means of mortality among CSE patients	RR (95% CI)	P value (significance tests of RR=1)	I² (%)	RD (95% CI)	P value (significance tests of RD=0)	I² (%)
In-hospital mortality	31	1668	3753	42.30%	20.00%	2.09 (1.81 to 2.42)	0.000	49.8	0.21 (0.17 to 0.26)	0.000	71.0
28-day or 30-day mortality	17	1161	2463	42.85%	19.88%	2.23 (1.83 to 2.72)	0.000	63.6	0.23 (0.15 to 0.30)	0.000	79.1
21-day mortality	1	161	117	52.20%	14.50%	3.59 (2.26 to 5.71)	0.000	–	0.38 (0.28 to 0.48)	0.000	–
14-day mortality	4	84	287	45.09%	27.01%	1.70 (1.24 to 2.35)	0.001	0.0	0.18 (0.06 to 0.31)	0.003	0.0
6-day or 7-day mortality	3	149	372	25.90%	6.57%	3.68 (2.32 to 5.83)	0.000	0.0	0.18 (0.11 to 0.26)	0.000	0.0
Mortality attributable to infection	8	391	778	43.30%	17.45%	2.74 (1.97 to 3.81)	0.000	58.3	0.27 (0.15 to 0.38)	0.000	79.5
Mortality in ICU	4	1035	824	58.83%	50.50%	1.17 (1.08 to 1.28)	0.000	0.0	0.09 (0.04 to 0.14)	0.000	0.0
30-day mortality in ICU	1	244	263	28.90%	11.00%	2.60 (1.75 to 3.87)	0.000	–	0.18 (0.11 to 0.25)	0.000	–

CRE, carbapenem-resistant Enterobacteriaceae; CSE, carbapenem-susceptible Enterobacteriaceae; ICU, intensive care unit.