Table 11.
The Effect of Growth Hormone Therapy on Quality of Life of Patients after Traumatic Brain Injury (TBI)
| Author | Design | Severity | No. of patients with treatment | No. of patients without treatment | Treatment beginning and length (months) | QoL-AGHDA | QoLBI | p value in the treated group from baseline | p value between treated and untreated groups |
|---|---|---|---|---|---|---|---|---|---|
| Moreau et al.33 | Cohort study | All severities GCS: 8.1 (SD: 5.1) | 23 | 27 | Chronic, 12 | X | Improvement | ||
| Tanriverdi et al.8 | Case report | No GCS Assessed | 2 | Chronic, 6 | X | Improvement | |||
| Gardener et al.36 | Cross-sectional registry | No GCS assessed | 161 | Chronic, 12 months | X |
Quality of life (QoL) of patients was assessed by Quality of Life Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA) questionnaire and the Quality of Life after Brain Injury (QOLBI) questionnaire. Statistical significance is indicated at p < 0.05.
GCS, Glasgow Coma Scale.