Table 3.

Univariate and multivariate adjusted logistic regression analysis of NPC1L1 gene SNPs and the risk of PTVD.

Polymorphism	Model	Crude			Multivariate*
		OR	95% CI	P	OR	95% CI	P
rs11763759 T>C	Codominant (TT/TC/CC)	0.99	0.70–1.41	0.951	0.995	0.70–1.43	0.976
	Recessive (CC/TT+TC)	1.15	0.25–8.07	0.866	1.20	0.25–8.43	0.832
	Dominance (TT/CT+CC)	0.98	0.68–1.44	0.916	0.98	0.68–1.45	0.934
rs4720470 C>T	Codominant (CC/CT/TT)	1.18	0.99–1.42	0.071	1.19	0.99–1.43	0.062
	Recessive (TT/CT+CC)	1.73	1.13–2.72	0.014	1.74	1.14–2.74	0.013
	Dominance (CC/CT+TT)	1.12	0.88–1.41	0.366	1.12	0.89–1.43	0.330
rs2072183 G>C	Codominant (GG/GC/ CC)	0.89	0.75–1.05	0.168	0.89	0.75–1.06	0.181
	Recessive (CC/GG+GC)	0.88	0.64–1.24	0.464	0.88	0.63–1.23	0.450
	Dominance (GG/CC+GC)	0.84	0.65–1.07	0.157	0.84	0.66–1.08	0.180
rs2073547 A>G	Codominant (AA/AG/GG)	0.88	0.75–1.05	0.161	0.89	0.74–1.05	0.168
	Recessive (GG/AA+AG)	0.87	0.63–1.22	0.417	0.86	0.62–1.21	0.390
	Dominance (AA/AG+GG)	0.84	0.66–1.07	0.163	0.85	0.66–1.08	0.190

^*Adjusted for age and sex. NPC1L1, Niemann-Pick C1-like 1; PTVD, premature triple-vessel disease; OR, odds ratio; CI, confidence interval.