Table 1.
Baseline characteristics of study cohort.
| Variable | Total (n = 2,118) |
|---|---|
| Age (years) | 48 ± 16 |
| Male gender | 1,255 (59%) |
| Primary kidney disease | |
| Chronic glomerulonephritis | 1,252 (59%) |
| Diabetic nephropathy | 347 (16%) |
| Hypertensive nephrosclerosis | 284 (13%) |
| Others | 232 (11%) |
| Comorbid conditions | |
| History of cardiovascular disease | 455 (22%) |
| History of DM | 522 (25%) |
| BMI (kg/m2) | 21.6 ± 3.2 |
| SBP (mmHg) | 139 ± 18 |
| DBP (mmHg) | 85 ± 24 |
| Hemoglobin (g/L) | 106 ± 23 |
| Serum albumin (g/L) | 37.0 ± 5.08 |
| Calcium (mmol/L) | 2.25 ± 0.22 |
| Serum phosphorus (mmol/L) | 1.45 ± 0.43 |
| iPTH (pg/mL) | 235 (114, 406) |
| Cholesterol (mmol/L) | 4.9 (4.1–5.7) |
| Triglyceride (mmol/L) | 1.72 ± 1.41 |
| LDL-C (mmol/L) | 2.95 ± 1.03 |
| HDL-C(mmol/L) | 1.20 ± 0.55 |
| hs-CRP (mg/L) | 1.6 (0.5–5.1) |
| nPCR (g/kg/d) | 0.9 ± 0.3 |
| RRF (ml/min/1.73 m2) | 4 (2-17) |
| Baseline medications | |
| Phosphorus binders | 849 (40%) |
| Calcitriol | 635 (30%) |
| α-Ketoacid | 777(37%) |
The results are expressed as means ± SD for normal distributed continuous variables, median (25th percentile and 75th percentile) for skew continuous variables or number (%) for categorical variables.
BMI, body mass index; DBP, diastolic blood pressure; DM, diabetes mellitus; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high sensitive C-reactive protein; iPTH, intact parathyroid hormone; LDL-C, low-density lipoprotein cholesterol; nPCR, normalized protein catabolic rate; RRF, residual renal function; SBP, systolic blood pressure.