Table 3.
Changes in serum PTH, calcium, phosphorus levels, volume and the maximum diameter of parathyroid lesions in PHPT patients before and after MWA.
| Follow-up period | Serum PTH (pg/mL) | Serum calcium (mmol/L) | Serum phosphorus (mmol/L) | V (cm3) | Maximum diameter (cm) |
|---|---|---|---|---|---|
| Before MWA (n=20) | 122.35 (91.52, 266.90) | 2.72 ± 0.30 | 0.85 ± 0.16 | 0.71 (0.42, 3.04) | 1.87 (1.45, 2.50) |
| 20 min after MWA (n=20) | 48.35 (19.99, 93.82)*** | 2.64 ± 0.28 | 0.78 ± 0.16* | – | – |
| 4 h after MWA (n=20) | 35.36 (12.98, 76.32)*** | 2.61 ± 0.21* | 0.76 ± 0.29 | – | – |
| 1 day after MWA (n=20) | 48.10 (21.97, 67.00)*** | 2.35 ± 0.19*** | 1.05 ± 0.29** | – | – |
| 1 month after MWA (n=19) | 72.14 (44.57, 104.20)** | 2.35 ± 0.10*** | 1.03 ± 0.18** | 0.55 (0.30, 0.86)** | 1.25 (1.00, 1.70)** |
| 3 months after MWA (n=19) | 68.30 (58.96, 101.00)** | 2.37 ± 0.19** | 1.00 ± 0.14** | 0.26 (0.07, 0.40)** | 1.08 (0.74, 1.65)** |
| 6 months after MWA (n=11) | 67.69 (42.24, 82.26)** | 2.38 ± 0.11* | 0.95 ± 0.15 | 0.10 (0.03, 0.30)** | 0.86 (0.45, 1.34)* |
| 12months after MWA (n=8) | 59.61 (39.17, 66.95)* | 2.37 ± 0.15** | 1.06 ± 0.23* | 0.04 (0.00, 0.16)** | 0.50 (0.00, 1.10)* |
PTH, parathyroid hormone; PHPT, primary hyperparathyroidism; MWA, microwave ablation; V, volume of parathyroid glands; -, not reported; n means patient number.
Compared with preoperative levels, *P < 0.05, **P < 0.01, ***P < 0.001.
Normal reference ranges: serum PTH 15-65 pg/mL, serum calcium 2.10-2.55 mmol/L, serum phosphorus 0.81-1.45 mmol/.