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NGR1 attenuates H9c2 cardiomyocyte apoptosis induced by high glucose concentration. (A) TUNEL staining at ×400 magnification. High glucose concentration increased H9c2 cardiomyocyte apoptosis, but the effect was reduced by NGR1. (B) Pretreatment with NGR1 significantly reduced the apoptosis rate. Data are shown as the means ± SEM of three independent experiments, *p < 0.001 and # p < 0.001. LG, 5.5 mM glucose; HG, 30 mM glucose; NGR1, Notoginsenoside R1.
