Table 5. Effects of Bacillus-based probiotics on immune responses of weaned pigs1).
| Item | Dietary treatments | SEM | p-value | |
|---|---|---|---|---|
| CON | PRO | |||
| Day 7 | ||||
| Number of white blood cells (×103/μL) | 17.47 | 17.92 | 2.277 | 0.892 |
| CRP (ng/mL) | 152.98 | 282.30 | 56.45 | 0.167 |
| Cortisol (ng/mL) | 1.21 | 2.47 | 0.56 | 0.172 |
| TGF-β1 (pg/mL) | 590.85 | 987.28 | 139.03 | 0.092 |
| TNF-α (pg/mL) | 317.94 | 366.82 | 17.98 | 0.079 |
| IgA (ng/mL) | 72.17 | 66.71 | 5.89 | 0.527 |
| IgG (ng/mL) | 945.69 | 943.74 | 13.29 | 0.919 |
| IgM (ng/mL) | 234.02 | 199.70 | 43.52 | 0.589 |
| Day 14 | ||||
| Number of white blood cells (×103/μL) | 20.32 | 20.13 | 2.113 | 0.952 |
| CRP (ng/mL) | 149.88 | 191.47 | 43.33 | 0.529 |
| Cortisol (ng/mL) | 1.44 | 2.02 | 0.40 | 0.353 |
| TGF-β1 (pg/mL) | 636.03 | 1,095.56 | 153.67 | 0.089 |
| TNF-α (pg/mL) | 341.43 | 386.42 | 17.47 | 0.903 |
| IgA (ng/mL) | 88.17 | 80.53 | 9.59 | 0.586 |
| IgG (ng/mL) | 972.57 | 956.67 | 17.79 | 0.251 |
| IgM (ng/mL) | 161.92 | 182.53 | 26.49 | 0.594 |
1)
Each value presented as the least square mean of 5 replicates.
CON, control diet based on soy-bean meal diet; PRO, control + 0.01% Bacillus-based probiotics; CRP, C-reactive protein; TGF-β1, transforming growth factor-β1; TNF-α, tumor necrosis factor-α; IgA, immunoglobulin A; IgG, immunoglobulin G; IgM, immunoglobulin M.