Figure 3. . t-test comparison of methylation (%) means between genocide-exposed versus unexposed children and mothers, respectively.

Blue represents lower mean methylation in unexposed individuals, and red represents higher mean methylation in exposed individuals. Each dot represents an individual sample. Methylation (%) of significant (p < 0.05) CpGs in the top two genes (BCOR, PRDM8) that are consistently significant in the differentially methylated regions and intergenerational analysis is shown. There is a significant difference in methylation levels between exposed versus unexposed subjects in both children and mothers (p < 0.05). Both CpGs (cg15627188, cg05059566) showed higher methylation levels in those exposed to genocide.