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. 2021 Dec 1;9:746471. doi: 10.3389/fped.2021.746471

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Copyright © 2021 Vu, Donovan, Brink, Li, Gross, Dilger and Fleming.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Density plots with overlayed histograms showing smoothed distributions of organ weights of reference pigs stratified by (A–C) sex or (D) rearing environment. “Density” represents the function used to calculate the probability of getting a value between a range of values on the x-axis. The peaks of the density depict where values are concentrated over a given interval. The density plotted as percent of total body weight (BW) for (A) brain, n_male = 20, n_female = 8, (B) intestines n_male = 60, n_female = 15, and (C) liver n_male =8, n_female = 8. (D) A density plot of percent intestinal growth in artifically-reared (AR) and sow-reared (SR) artificial reference pigs, n_AR = 57, n_SR =18. (E) Absolute intestinal weight plotted as a function of PND (PND 1, n_sample = 3; PND 3, n_sample = 7; PND 7, n_sample = 6; PND 8, n_sample = 34; PND 14, n_sample = 6; PND 21, n_sample = 31; PND 22, n_sample = 7; PND 23, n_sample = 21; PND 28, n_sample = 11; PND 29, n_sample = 31) in artificially-reared reference animals indicates linear increase over time.