Table 6.
Clinical Outcomes in Adult Asthmatics by ICS Use
| Overall | Any ICS Use | No ICS Use | Odds Ratio (If Applicable) | 95% Confidence Interval | p value | |
|---|---|---|---|---|---|---|
| n=787 | n=301 | n=486 | ||||
| Age (years), Mean (SD) | 59.8 (16.4) | 63.5 (15.2) | 57.6 (16.7) | <0.001 | ||
| Sex (female), n (%) | 475 (60.4) | 193 (64) | 282 (58) | 0.10 | ||
| Race, n (%) | 0.26 | |||||
| Asian | 65 (8.3) | 26 (8.6) | 39 (8.0) | |||
| Black | 203 (25.8) | 71 (23.6) | 132 (27.2) | |||
| Other/Unknowna | 255 (32.4) | 91 (30.2) | 164 (33.7) | |||
| White | 264 (33.5) | 113 (37.5) | 151 (31.1) | |||
| Ethnicity, n (%) | 0.07 | |||||
| Hispanic/Latino | 171 (21.7) | 53 (17.6) | 118 (24.3) | |||
| Other | 43 (5.5) | 15 (5.0) | 28 (5.8) | |||
| Non-Hispanic or Latino | 573 (72.8) | 233 (77.4) | 340 (70.0) | |||
| Days on Ventilator, Mean (SD)b | 13.9 (15.2) | 15.0 (16.1) | 13.1 (14.6) | (−6.89, 2.96) | 0.43 | |
| Length of Stay (days), Mean (SD) | 9.65 (11.0) | 10.5 (12.2) | 9.10 (10.2) | (−3.08, 10.5) | 0.09 | |
| Ventilator Support, n (%) | 145 (18.4) | 60 (19.9) | 85 (17.5) | 1.17 | (0.81, 1.70) | 0.39 |
| Deaths, n (%) | 144 (18.3) | 61 (20.3) | 83 (17.1) | 1.15 | (0.79, 1.65) | 0.47 |
| Discharged on Oxygen, n (%) | 131 (16.6) | 64 (21.3) | 67 (13.8) | 1.62c | (1.10, 2.38) | 0.01 |
| ICU Admission, n (%) | 194 (24.7) | 81 (26.9) | 113 (23.3) | 1.22 | (0.87, 1.69) | 0.25 |
Notes: a31 Patients with “Unknown” race were grouped together with “Other”. bt-test was performed on patients who required ventilator support during admission. Patients without ventilator support were excluded from analysis. cRepresents adjusted odds ratio for age.
Abbreviations: SD, standard deviation; ICS, inhaled corticosteroids; ICS + LABA, inhaled corticosteroids plus long-acting beta agonist; ICU, intensive care unit.