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. 2021 Dec 14;15:92. doi: 10.1186/s13031-021-00384-3

Table 2.

Summary of conflict-related health research studies inside Syria, January 2011–December 2019

First author (Publication year) First & Last (Senior) authors’ country of institutional affiliation Type of institutional affiliation Description Theme (Subtheme) Study Period (month/year) Methodology Study Population Geographic focus Funding
Alasaad (2013) [8]

First: Syria, Switzerland, Spain

Last: N/A

First: academic Reviews YouTube and social media videos to describe leishmaniasis outbreaks in Deir ez-Zor. Health status January–March 2013 YouTube and Facebook video review, contact with local communities General population Deir ez-Zor Not reported
Ahmad (2014) [9]

First: UK

Last: N/A

First: academic Assesses the influences of neighborhood socioeconomic position and urban informal settlements on women’s health. Health determinants and risks April–May 2011 Key informant interviews, unstructured observations Professionals working with populations in informal communities; women in informal settlements Aleppo Institute of Health and Society, Newcastle University, UK
Hoetjes (2014) [10]

First: Netherlands

Last: Netherlands

First: humanitarian

Last: humanitarian

Documents results of a screening program and examines food security and factors affecting nutritional status amongst the Tal-Abyad population (Al-Raqqa), and describes MSF nutrition programs. Health status; humanitarian assistance, response or needs 2013 Mixed methods (middle-upper arm circumference screening; qualitative survey) IDPs living in schools Al-Raqqa Not reported
Rosman (2014) [11]

First: Israel

Last: Israel

First: academic/ military

Last: academic/ military

Reports on physician reviews of YouTube videos documenting a sarin attack to determine clinical presentation and review the management of a mass casualty event War strategies / alleged IHL violations August–September 2013 Physician review of YouTube videos Casualties of Ghouta sarin attack Damascus Not reported
Alshiekhly (2015) [12]

First: Syria

Last: Syria

First: academic

Last: academic

Evaluates feasibility of Facebook as a teaching modality for a course on medical emergencies in dental practice Health system (workforce) March–April 2014 Pre and post questionnaire Dental students Not reported None
Doocy (2015) [13]

First: USA

Last: Belgium

First: academic

Last: academic

Documents humanitarian needs and priorities among households in need of assistance in accessible communities Humanitarian assistance, response or needs April–June 2014 Needs assessment General population Predominantly government-controlled areas (Aleppo, As-Sweida, Damascus, Dara’a, Al-Hasakeh, Homs, Lattakia, Rural Damascus, Tartous) Humanitarian assistance programs
Doocy (2015) [14]

First: USA

Last: USA

First: academic

Last: academic

Describes trends in internal displacement and analyzes the association between displacement and household well-being and humanitarian needs. Humanitarian assistance, response or needs March 2011–June 2014 Review of published IDP estimates; needs assessment General population National Not reported
Guha-Sapir (2015) [15]

First: Belgium

Last: Lebanon

First: academic

Last: academic

Documents direct conflict-related deaths of women and children using VDC data. Mortality; war strategies / alleged IHL violations March 2011–January 2015 VDC data analysis Civilians National emBRACE—Building resilience amongst communities in Europe & Chatham House
Price (2015) [16]

First: USA

Last: USA

First: humanitarian

Last: humanitarian

Applies capture - recapture methods to data from four sources to estimate mortality, and describes the issues associated with accurately documenting mortality estimates in conflict settings Mortality December 2012–March 2013 Multiple systems estimation / capture -recapture Civilians and combatants Homs, Hama Not reported
Sekkarie (2015) [17]

First: USA

Last: USA

First: clinical

Last: academic

Explores the impact of conflict on dialysis services Health system (service provision, workforce) 2013 Key informant Interviews Dialysis facility administrators, providers and patients Non-government-controlled areas (Aleppo, Homs, Idlib) Not reported
Tajaldin (2015) [18]

First: USA

Last: USA

First: academic

Last: academic

Compares polio case rates using laboratory versus clinical case definitions and different surveillance systems Health system (information systems); health status 2013–2014 Analysis of EWARS and EWARN data General population National Not reported
Trelles (2015) [19]

First: Belgium

Last: Belgium

First: humanitarian

Last: humanitarian

Reports on surgical cases and intraoperative mortality rates at an MSF field hospital Humanitarian assistance, response or needs September 2012–January 2014 Analysis of MSF programme data Surgical patients Jabal Al Akrad, Latakia Northwest Syria Médecins Sans Frontières-Operational Centre, Belgium.
Charlson (2016) [20]

First: Australia, USA

Last: Australia, USA

First: academic

Last: academic

Estimates prevalence of depression and PTSD and models likely current and future mental health service requirements Health status; Health system (service provision, workforce) Global Burden of Disease Study 2010, modelling for period 2015–2030 Global Burden of Disease (GBD) methodology and modelling General population National Queensland Department of Health, Australia
El-Khani (2016) [21]

First: UK

Last: UK

First: academic

Last: academic

Examines feasibility of the “bread wrapper approach” which involves distribution of psychological support information on leaflets inserted into bread wraps and using the bread wraps to circulate questionnaires assessing the usefulness of the information provided. Humanitarian assistance, response or needs Not reported Questionnaire General population Northern Syria next to the borders with Turkey The University of Manchester’s ESRC Transformative Research Prize Committee
Elsafti (2016) [22]

First: Qatar, Egypt

Last: Belgium

First: clinical

Last: academic

Documents the family, educational, and health status of Syrian children and associated humanitarian needs Health status; humanitarian assistance, response or needs May 2015 Needs assessment Children less than 15 years old Aleppo, Hama, Idlib, Lattakia None
Ismail (2016) [23]

First: UK

Last: Lebanon

First: academic

Last: academic

Describes trends in tuberculosis, measles and polio case numbers in Syria and challenges of disease surveillance in the conflict context. Health system (information systems); health status Peer-reviewed analysis (2005–2015), EWARN & EWARS analysis (2014–2015) Analysis of EWARN, EWARS data General population National Not reported
Jefee-Bahloul (2016) [24]

First: USA

Last: USA

First: academic

Last: academic

Examines attitudes of Syrian healthcare providers towards Store & Forward tele-mental health consultations Health system (service provision) Not reported Online survey Syrian health-care professionals affiliated with humanitarian NGOs Aleppo, Damascus, Idlib, Othersa Not reported
Mowafi (2016) [25]

First: USA

Last: France

First: academic

Last: humanitarian

Assesses the functional status and capacity of trauma hospitals Health system (service provision, workforce) February–March 2015 Survey Hospitals providing secondary or tertiary surgical care in non-government-controlled areas Aleppo, Damascus (non-government-controlled area), Dara’a, Hama, Homs, Idlib, Lattakia, Quneitra, Rural Damascus Yale University & UOSSM.
Sparrow (2016) [26]

First: USA

Last: Australia

First: academic

Last: academic

Compares two infectious disease surveillance systems, the Ministry of Health-run EWARS system and the independent, non-governmental EWARN Health system (information system); health status 2014–2015 Analysis of EWARS and EWARN data General population National Not reported
Al-Saadi (2017) [27]

First: Syria

Last: Syria

First: academic

Last: academic

Reports prevalence and risk factors of psychological distress among medical students in Damascus Health status; Health system (workforce) November 2015 Online questionnaire Second to sixth-year medical students at Damascus University Damascus None
Alsaied (2017) [28]

First: USA

Last: Canada, Qatar

First: clinical

Last: academic, clinical

Reports on the operations of UOSSMb primary care clinics in Opposition Territories and reasons for consultations Humanitarian assistance, response or needs; health status January 2014–December 2015 Retrospective administrative database review Patients seen at 10 primary care centers Opposition-controlled areas (Aleppo, Deir ez-Zor, Hama, Homs, Idlib, Lattakia) None
Arafat (2017) [29]

First: Syria

Last: Syria

First: clinical

Last: academic

Describes differences in patterns of injury and mortality rates among patients with penetrating abdominal injuries at Damascus Hospital Health status October 2012–June 2013 Retrospective review of records Patients with penetrating abdominal injuries Damascus None
Baaity (2017) [30]

First: Syria

Last: Syria

First: academic

Last: academic

Reports the prevalence of extended spectrum β lactamases of E. coli in isolates from patients in Al-Assad Teaching Hospital, Lattakia Health status October 2014–November 2016 Analysis of data regarding clinical isolates Patients in Al-Assad teaching hospital Lattakia Not reported
Cummins (2017) [31]

First: Not stated

Last: Turkey

First: humanitarian

Last: humanitarian

Aims to understand the impact of providing food kits in Idlib and how it disturbs the food market, and proposes market-based approach as an alternative for food aid provision. Humanitarian assistance, response or needs 2016 Interviews Community members in Idlib (Darkoush and Salquin) Idlib UK Department for International Development (DFID) through the Urban Crises Learning Fund.
Diggle (2017) [32]

First: UK

Last: UK

First: humanitarian

Last: academic

Reflects on operational experiences and analyses humanitarian health response data collected in contested and opposition-held areas of Syria Mortality; health status; humanitarian assistance, response or needs 2013–2014 Analysis and review of data from multiple operational databases Civilians & combatants Contested and opposition-controlled areas (governorates not specified) None
Doocy (2017) [33]

First: USA

Last: USA

First: academic

Last: academic

Identifies humanitarian needs and priorities among displaced and female headed households in government-controlled areas Humanitarian assistance, response or needs April–June 2016 Needs assessment Displaced & female headed households Government-controlled areas (Aleppo, As-Sweida, Damascus, Dara’a, Hama, Al-Hasakeh, Homs, Lattakia, Rural Damascus, Tartous) US-based international nongovernmental organization
Doocy (2017) [34]

First: USA

Last: Turkey

First: academic

Last: humanitarian

Examines the effectiveness of three assistance programs (in-kind food commodities, food vouchers, unrestricted vouchers) in improving food security in northern Syria. Humanitarian assistance, response or needs; Health determinants and risks September–December 2014, May/June 2015 Serial household surveys, shopkeeper survey and analysis of program monitoring data Beneficiary households; shopkeepers participating in the voucher program Idlib GOAL
Elamein (2017) [35]

First: Turkey

Last: Turkey, Egypt

First: UN agency

Last: UN agency, academic

Describes the first operational use of the Monitoring Violence against Health Care (MVH) tool to report real-time incident data for attacks on healthcare infrastructure, workers and patients War strategies / alleged IHL violations; health system (service provision; workforce) November 2015–December 2016 Analysis of MVH data Healthcare workers, health service users Aleppo, Al-Raqqa, Damascus, Dara’a, Deir ez-Zor, Hama, Homs, Idlib, Lattakia, Quneitra, Rural Damascus None
Fouad (2017) [36]

First: Lebanon

Last: Lebanon

First: academic

Last: academic

Reports on attacks on healthcare and experiences of health workers inside Syria War strategies / alleged IHL violations; health system (workforce; service provision) Not reported Mixed methods study (quantitative data analysis, consultations, testimonials) Health workers National IDRC; American University of Beirut
Fujita (2017) [37]

First: Japan

Last: Sweden

First: academic

Last: academic

Presents daily time series analysis of violent deaths in Syria, including temporal and spatial analysis, and compares trends with those of violent and non-violent deaths in the non-conflict context of England Mortality 1200-day period commencing 500 days post conflict onset Secondary analysis and modelling of Violations Documentation Center data Civilians and military personnel Aleppo, Damascus, Dara’a, Homs, Idlib Bilateral Joint Research Project between JSPS, Japan, and FRS-FNRS, Belgium. Grants-in-Aid for Scientific Research from MEXT Japan
Hawat (2017) [38]

First: Syria

Last: Syria

First: academic

Last: academic

Reviews the epidemiology of cutaneous and visceral leishmaniasis in Lattakia and examines the effects of the Syrian conflict on incidence Health status 2006–2016 Analysis of Leishmaniasis and Contagious Diseases Centre data for new cases of leishmaniasis General population Lattakia Not reported
Mohammad (2017) [39]

First: Syria

Last: Canada

First: academic

Last: clinical, academic

Assesses asthma prevalence, asthma control and quality of life among those with diagnosed asthma;

Among non-asthmatics, estimates prevalence of respiratory symptoms, PTSD symptoms and other chronic disease co-morbidities.

Health status Not reported Cross-sectional survey IDPs in Al-Herjalleh shelter aged > = 5 years Damascus Syrian Private University
Sahloul (2017) [40]

First: USA

Last: USA

First: academic

Last: clinical

Examines quality of cancer care and needs in government-controlled areas versus besieged areas, and provision of care in general clinics compared with specialized cancer care clinics. Health system (service provision, workforce); war strategies / alleged IHL violations Not reported Cross-sectional survey Oncologists and surgeons working in cancer clinics, and general physicians Government-controlled areas (Damascus, Lattakia, Homs, and West Aleppo) and besieged areas (East Ghouta, East Aleppo, and Idlib) Not reported
van Berlaer (2017) [41]

First: Belgium

Last: Belgium

First: academic

Last: academic

Documents diagnoses, injuries and comorbidities in children in Northern Syria Health status; humanitarian assistance, response or needs May 2015 Cross-sectional household survey Children younger than 15 years Aleppo, Hama, Idlib, Lattakia None
Abbas (2018) [42]

First: Syria

Last: Syria

First: academic

Last: academic

Examines efficacy and feasibility of peer- led versus professional-led training in basic life support course for medical students Health system (workforce) April 2016 Randomized controlled trial Medical students in pre-clinical years at Syrian Private University Damascus None
Albaroudi (2018) [43]

First: Syria

Last: Syria

First: academic

Last: academic

Examines prevalence of iron deficiency and iron deficiency anemia in children and socioeconomic associations, and effectiveness of oral iron supplements Health status; health determinants and risks

1) Retrospective part: November 2011–November 2015

2) Prospective part: 2 month period, not specified

Retrospective medical record review; parental questionnaire & clinical data analysis Children seen at primary care clinics at the Children’s Hospital in Damascus Damascus Damascus University
Ballouk (2018) [44]

First: Syria

Last: Syria

First: academic

Last: academic, government

Assesses gingival health status in children aged 8–12 years in Damascus city Health status September 2016–January 2017 Cross-sectional, school-based oral health survey Children aged 8–12 years Damascus None
Chen (2018) [45]

First: USA

Last: USA

First: academic

Last: academic

Estimates the number of unique identifiable deaths in the Syrian conflict by deduplicating four datasets Mortality; war strategies and alleged IHL violations March 2011–April 2014 Unique entity estimation using mortality data from VDC, SNHR, CSR-SY, SSc Civilians and combatants Not reported National Science Foundation (NSF), Amazon Research Award, Laboratory for Analytic Sciences (LAS).
Darwish (2018) [46]

First: Syria

Last: Syria

First: academic

Last: academic

Reviews pediatric chest injuries treated in the Mouassat University Hospital in Damascus before and during the Syrian crisis Health status January 2005–December 2016 Hospital record review Pediatric chest trauma patients Damascus None
de Lima Pereira (2018) [47]

First: Syria

Last: Netherlands

First: humanitarian

Last: humanitarian

Assesses vaccine-preventable disease risk and vaccination needs, and vaccination coverage following an immunization program Humanitarian assistance, response or needs; health status June–September 2015 Cross-sectional household survey Children < 5 years old Aleppo None
Doocy (2018) [48]

First: USA

Last: USA

First: academic

Last: academic

Assesses humanitarian needs in government-controlled areas of Syria Humanitarian assistance, response or needs April – June 2016 Needs assessment General population Government-controlled areas (Aleppo, As-Sweida, Damascus, Dara’a, Hama, Al-Hasakeh, Homs, Lattakia, Rural Damascus, Tartous) US-based international nongovernmental organization
Footer (2018) [49]

First: USA

Last: USA

First: academic

Last: academic

Explores the impact of the Syrian conflict on health workers and healthcare in opposition-controlled areas and challenges faced, including in responding to chemical weapons attacks Health system (service provision, workforce); war strategies / alleged IHL violation October 2014 (Gaziantep), July–August 2017 (online) Semi-structured interviews Health-care professionals with experience in opposition-controlled areas of Syria Opposition- controlled areas (governorates not specified) MacArthur Foundation
Garry (2018) [50]

First: UK

Last: UK

First: academic

Last: academic

Explores factors impacting provision of healthcare for NCDs in opposition-controlled Syria Humanitarian assistance, response or needs June–August 2017 Semi-structured interviews Humanitarian healthcare staff or Syrian health workers from opposition-controlled / contested areas Opposition-controlled areas (governorates not specified) UK Research and Innovation (Global Challenges Research Fund)
Guha-Sapir (2018) [51]

First: Belgium

Last: USA

First: academic

Last: academic

Reports demographic, spatial, and temporal patterns of direct deaths among civilians and opposition combatants using VDC data Mortality; war strategies / alleged IHL violations March 2011–December 2016 VDC data analysis Civilians and combatants Non-government-controlled areas (governorates not specified) None
Haar (2018) [52]

First: USA

Last: USA

First: academic

Last: academic

Describes a standardized field survey tool for documenting attacks on healthcare, and compares this dataset to PHR’s database that uses open sources to track attacks on health facilities War strategies / alleged IHL violations; health system (service provision, workforce) 2016 Development of prospective surveillance methodology, standardized reporting questionnaire NA Aleppo, Hama, Homs, Idlib MacArthur Foundation, the Oak Foundation, Berkeley Research Impact Initiative
Idris (2018) [53]

First: Syria

Last: Syria

First: academic

Last: academic

Reports prevalence of cigarette smoking among university students and examines the impact of war on smoking behavior Health determinants and risks May 2015 Online cross-sectional survey Undergraduate students at Damascus University. Damascus None
Khamis (2018) [54]

First: Syria

Last: Lebanon

First: government

Last: academic

Reports National AIDS Program data and examines how the war affected HIV surveillance and voluntary counselling and testing Health status; health system (service provision) 2010–2016 Secondary analysis of National AIDS Program surveillance data General population National Not reported
Kubitary (2018) [55]

First: Syria

Last: Syria, France

First: academic

Last: academic

Examines validity of the Arabic version of the two-question Quick Inventory of Depression (QID-2-Ar) in Syrian multiple sclerosis patients. Health status Not reported Cross-sectional study Multiple sclerosis patients aged 18–60 years seen at two hospitals Damascus None
Kubitary (2018) [56]

First: Syria

Last: France, Syria

First: academic

Last: academic

Examines the effects of Therapy by Repeating Phrases of Positive Thoughts (TRPPT) on PTSD, Sleep Disorder and War Experiences among school children and adolescents Health systems (service provision); health status Not reported Clinical trial Children & adolescents aged 13–17 years Damascus Not reported
Meiqari (2018) [57]

First: Netherlands

Last: Netherlands

First: humanitarian, academic

Last: humanitarian

Describes the impact of the war on child health in Tal Al-Abyad and Kobane, using available medical and humanitarian data from Médecins Sans Frontières Health status; humanitarian assessment, response or needs April 2013–September 2016 Analysis of MSF clinical data and reports Children < 5 years old who attended an MSF facility Aleppo, Al-Raqqa Not reported
Morrison (2018) [58]

First: UK

Last: N/A

First: academic Reports the experiences and challenges of health service delivery under siege Health system (service provision); war strategies / alleged IHL violations Mid-2016 Interviews and focus group discussions Interim Council and healthcare professionals in four besieged urban areas Opposition-controlled areas (Aleppo, Damascus) DFID’s Urban Crises Programme
Othman (2018) [59]

First: Not stated

Last: Australia

First: independent

Last: academic

Evaluates the impact of a six-month programme to address organizational stressors and promote staff-care and social support Health determinants and risks; health system (workforce) Not reported Evaluation research/ Implementation research Staff working for a psychosocial support organization Non-government-controlled areas (Idlib) Not reported
Perkins (2018) [60]

First: UK

Last: Syria

First: academic

Last: academic

Reports the incidence of psychological symptoms among school-aged children in Damascus and Lattakia Health status Not reported Cross-sectional study School children (8–15 years old) Damascus, Lattakia Not reported
Rehman (2018) [61]

First: Austria

Last: Germany; Austria

First: academic

Last: academic, clinical

Describes the leishmaniasis surveillance control program Health status

November 2014–

February 2016

Molecular–epidemiologic survey of cutaneous leishmaniasis in sentinel sites General population (including IDPs) Northern Syria (Aleppo, Idlib, Hama, Al-Raqqa, and Al-Hasakeh) USAID & DFID
Rodriguez-Llanes (2018) [62]

First: Belgium

Last: USA

First: academic

Last: academic

Reports demographic characteristics of victims of chemical weapons attacks War strategies / alleged IHL violations; mortality March 2011–April 2017 VDC data analysis Deceased victims of chemical weapons attacks Non-government-controlled areas (Aleppo, Damascus, Hama, Idlib) None
Sawaf (2018) [63]

First: Syria

Last: Syria

First: academic

Last: academic

Explores medical students’ attitudes and factors affecting their specialty choices and career plans Health system (workforce) August 2016 Self- administered questionnaire Medical students at three universities in Damascus Damascus Syrian Private University
Sikder (2018) [64]

First: USA

Last: Jordan

First: academic

Last: independent

Assesses the effectiveness of a multilevel risk reduction intervention in maintaining Free Chlorine Residual in household drinking water Humanitarian assessment, response or needs January 2018 Cross-sectional study using interviews & observations; water quality testing Chlorination station operators, well owners, households, Methology Opposition-controlled areas in southern Syria (governorates not specified) WoS (Amman hub) WASH Sector, UNICEF, UNICEF/NYC and Tufts University
Sikder (2018) [65]

First: USA

Last: Jordan

First: academic

Last: UN agency

Examines WASH access and needs in opposition controlled southern Syria Humanitarian assessment, response or needs June/July 2016–February 2017 Cross-sectional household surveys & water quality testing Households Opposition-controlled areas (Dara’a, Quneitra) WoS (Amman hub) WASH Sector
Turk (2018) [66]

First: Syria

Last: USA

First: academic

Last: academic

Assesses medical students attitudes toward research Health system (workforce) Not reported Self-administered questionnaire Medical students at University of Damascus Damascus None
Wong (2018) [67]

First: USA

Last: USA

First: academic

Last: clinical

Reviews attacks on ambulances War strategies / alleged IHL violations; health system (service provision) January 2016–December 2017 Secondary data analysis on individual attacks reported by SNHR NA National None
Ahmad (2019) [68]

First: UK

Last: UK

First: academic

Last: academic

Examines perceptions of married women living in low-income formal and informal neighborhoods in Aleppo on the effects of neighbourhood on their health and well-being Health determinants and risks April–June 2011 Semi-structured interviews Married women living in informal and low-income formal neighbourhoods Aleppo European Commission FP7 programme grants MedCHAMPS and RESCAP-MED
Abu Salem (2019) [69]

First: Lebanon

Last: Lebanon

First: academic

Last: academic

Uses VDC data to confirm conflict events and identify fake news in FA-KES, a fake news dataset Mortality Not reported Analysis of news articles and reports on incidence of deaths compared to VDC dataset General population National American University of Beirut
Alaryan (2019) [70]

First: Syria

Last: Syria

First: academic

Last: academic

Reports on prescription drug misuse in Damascus and Damascus countryside during the conflict Health system (medical products) December 2016–March 2017 Cross-sectional survey Community pharmacists Damascus and Rural Damascus Not reported
Alhaffar (2019) [71]

First: Syria

Last: Syria

First: academic

Last: clinical

Examines prevalence of burnout syndrome among resident physicians in training Health system (workforce) July 2018 Online questionnaire Resident physicians in training from 12 hospitals in 8 governorates who spent at least one year in a residency program approved by the Syrian Commission of the Medical Specialties. Damascus, Aleppo, Lattakia, Tartous, Dara’a, Rural Damascus, Hama, Homs Not funded (self-funded)
Alhaffar (2019) [72]

First: Syria

Last: Syria

First: academic

Last: academic

Examines the prevalence of caries and oral health status among school children in Damascus, and associations with socio-economic status Health status; Health determinants and risks September–November 2017 School-based survey (questionnaire and clinical examination) Seventh-grade school children in 10 randomly selected schools covering Damascus city Damascus Not funded (self-funded)
Alhammoud (2019) [73]

First: Qatar

Last: UK

First: clinical

Last: clinical

Reports the experience of one field hospital in Aleppo providing treatment of open shaft fractures Health system (service provision) July 2011–July 2016 Retrospective medical record review Patients with open long bone fractures managed with external fixation Aleppo Not reported
Alothman (2019) [74]

First: Syria

Last: India

First: academic

Last: academic

Reports on war injury presentations to Hama National Hospital Health system (service provision) 2017 Retrospective medical record review War injured patients received by Hama National Hospital Hama Not reported
Ballouk (2019) [75]

First: Syria

Last: Syria

First: academic

Last: academic, government

Examines prevalence of dental caries among school-aged children in Damascus city Health status September 2016–January 2017. School based oral health survey (clinical examination) School children aged 8–12 years and resident in Damascus city during the study period Damascus Not funded (self-funded)d
Blackwell (2019) [76]

First: USA

Last: not stated

First: humanitarian

Last: humanitarian

Examines the impact of a cash-based assistance program on women’s empowerment and violence against women Humanitarian assessment, response or needs; health status March–August 2018 Semi-structured interviews Woman aged 18–59 who received a cash payment over a three-month period Al-Raqqa UK Department for International Development (DFID)
Douedari (2019) [77]

First: UK

Last: UK

First: academic

Last: academic

Examines perceptions of local health providers and service users regarding health system governance, roles and relationships of institutional actors, and challenges and potential solutions Health system (governance) July–August 2016 Key informant interviews Health system providers from health directorates, humanitarian NGOs, donors, and service-users Opposition-controlled provinces (Aleppo, Dara’a, Hama, Idlib, Rural Damascus) Chevening Scholarships
Duclos (2019) [78]

First: UK

Last: UK

First: academic

Last: academic

Examines cross-border humanitarian assistance and the challenges encountered by humanitarian health actors delivering health care in North-West Syria (Turkish border) Humanitarian assessment, response or needs; health system (service provision) September 2017 Mixed methods, including key informant interviews, desk reviews and expert consultations Humanitarian aid professionals in Turkey-based organizations operating in North-West Syria, WHO-Turkey staff members and members of Syrian health directorates. North-West Syria London School of Hygiene and Tropical Medicine, Department of Infectious Disease Epidemiology, and the International Development Research Center (IDRC)
Falb (2019) [79]

First: USA

Last: USA

First: humanitarian

Last: humanitarian

Examines associations between depressive symptoms and their potential risk factors (including stressors, intimate partner violence) Health status; health determinants and risks March–April 2018 Cross-sectional survey Married women who participated in a cash transfer program Al-Raqqa UK Department for International Development (DFID)
Fardousi (2019) [80]

First: Lebanon, UK

Last: UK, Singapore

First: academic

Last: academic

Examines perspectives of healthcare workers on issues of safety, resource management and handling of mass casualties during siege Health system (workforce, service provision); war strategies / alleged IHL violations Not stated Key informant interviews Syrian healthcare workers and service users who experienced siege in Aleppo in 2016 or Ghouta (Rural Damascus) in 2013–2017 Aleppo, Rural Damascus Chevening Scholarships
Fradejas-Garcia (2019) [81]

First: Spain

Last: N/A

First: academic Explores experiences of remote cross-border operations Humanitarian assessment, response or needs Not reported Ethnographic study through interviews Aid workers and organizations – UN agencies, international NGOs and Syrian NGOs – providing relief assistance to Syria remotely Turkish border city of Gaziantep Not reported
Hallak (2019) [82]

First: Turkey

Last: Turkey

First: academic

Last: academic

Examines optimal shelter locations for IDPs Humanitarian assessment, response or needs December 2017–February 2018 Needs assessment using focus group discussions, key informant interviews and questionnaire with direct beneficiaries; mathematical modelling Direct beneficiaries in 26 sub-districts within Idlib Idlib Not reported
Hamid (2019) [83]

First: Syria

Last: Syria

First: academic

Last: academic

Compares dental and gingival status among children with and without PTSD Health status Not reported Case control study Children (9–14 years old) who attended psychiatry department (cases) or dental service (controls) Damascus Damascus University
Hamzeh (2019) [84]

First: Syria

Last: Syria

First:, academic

Last: academic

Assesses knowledge and awareness of diabetes mellitus and its complications and effects of the conflict on care-seeking behavior among diabetes patients in Damascus Health status; health determinants and risks August–November 2017 Questionnaire Diabetes mellitus patients attending clinics at the four main hospitals in Damascus Damascus Not funded
Jamal (2019) [85]e

First: UK

Last: Lebanon

First: academic

Last: academic

Examines the UNRWA health system and factors contributing to its resilience and enabling ongoing delivery of services to Palestinian refugees inside Syria during the crisis Health system (service provision, governance, medical products, workforce) February–August 2017 Key informant interviews, group model building sessions UNRWA clinical and administrative professionals engaged in health service delivery for Palestinian refugees in Syria over the course of the conflict Damascus, Jaramana (Rural Damascus), City Center Polyclinicf and Aleppo Wellcome Trust
Mic (2019) [86]

First: Turkey

Last: Turkey

First: academic

Last: academic

Examines optimal locations for primary health care centers in Idlib to allow services to the greatest number of people Humanitarian assessment, response or needs March–May 2018 Needs assessment using focus group discussions, key informant interviews and questionnaire with direct beneficiaries; mathematical modelling Direct beneficiaries in 23 sub-districts within Idlib Idlib Çukurova University (Adana, Turkey)
Mohammad (2019) [87]

First: Syria

Last: USA

First: academic

Last: academic

Evaluates effectiveness of personalized supervision of residents on improving prescribing for asthma management, and effectiveness of mobile video training for inhaler technique Health system (service provision) April–May 2018 Clinical audits; evaluation of efficacy of video-mobile education Asthma patients at internal medicine clinic in public hospital in Damascus Damascus Not reported
Muhjazi (2019) [88]

First: Egypt

Last: UK

First: UN agency

Last: humanitarian

Reports cutaneous leishmaniasis epidemiology over the course of the war Health status; Health system (information system) 2007–2010, 2011–2018 Secondary data analysis of 1) MOH routine surveillance system, 2) EWARS, 3) MENTOR Initiative data General population National Not funded
Okeeffe (2019) [89]

First: Syria

Last: Netherlands

First: humanitarian

Last: humanitarian

Describes blast-wound cases admitted to an MSF supported district hospital during the Raqqa military offensive and the first months of the post offensive period. Health status; Health system (service provision); humanitarian assessment, response, and needs June 2017–March 2018 Retrospective chart review New blast-wound injured cases admitted to MSF-district hospital in Al-Raqqa in the offensive (June–October 2017) or post offensive period (October 2017–March 2018) Al-Raqqa Not funded
Ri (2019) [90]

First: USA

Last: USA

First: academic

Last: academic

Compares trends of attacks on healthcare and civilian casualites to assess feasibility of using publicly available data on attacks on healthcare facilities to describe population-level violence Mortality; War strategies / alleged IHL violations March 2011–November 2017 Secondary analysis of publicly available data from: VDC (civilian casualties), PHR (attacks on healthcare facilities), UNHCR (registered Syrian refugees) Civilians National Not funded
Roumieh (2019) [91]

First: Syria

Last: Syria

First: academic

Last: academic

Assesses prevalence of postpartum depression among Syrian women in Damascus and examines associated risk factors Health status; Health determinants and risks January–December 2017 Cross-sectional questionnaire Postpartum women attending 8 primary healthcare centers in Damascus Damascus Damascus University
Terkawi (2019) [92]

First: USA, Saudi Arabia

Last: Saudi Arabia

First: humanitarian, academic, clinical, thinktank/ research organization

Last: academic

Assesses disease burden and clinical presentations of children and adolescents attending a healthcare center in Atmeh district, Idlib Health status February–December 2017 Clinical data analysis Children and adolescents attending healthcare center in Atmeh district Idlib Not funded
Terkawi (2019) [93]

First: USA, Saudi Arabia

Last: Saudi Arabia

First: humanitarian, academic, clinical, thinktank/ research organization

Last: academic

Examines health status and barriers to accessing antenatal care among pregnant women in Northwestern Syria Health system (service provision); health status; health determinants and risks February–December 2017 Medical record review; cross-sectional survey Pregnant women attending healthcare centers in Atmeh district for antenatal care Idlib Not funded
Vernier (2019) [94]

First: Syria

Last: UK

First: humanitarian

Last: humanitarian

Assesses health status and mortality among IDPs who recently arrived to Ein Issa camp in Al-Raqqa Health status; mortality; humanitarian assessment, response or needs; health determinants and risks November 2017 Cross-sectional survey IDPs who had arrived at Ein Issa camp since October 2017 Al-Raqqa MSF
Youssef (2019) [95]

First: Syria

Last: Lebanon

First: academic

Last: academic

Examines the epidemiology of visceral and cutaneous leishmaniases in Lattakia prior to and during the conflict Health status 2008–2016 Registry data analysis General population Lattakia The American Society of Tropical Medicine and Hygiene (ASTMH) assisted with the publication expenses
Ziveri (2019) [96]

First: Belgium

Last: Belgium

First: humanitarian

Last: independent

Examines impact of a psychosocial support program on the well-being and agency of Syrian farmers receiving livelihood support Humanitarian assessment, response or needs April–August 2017 Randomized control trial among Syrian farmers Farming households from ten randomly selected villages who fulfilled inclusion criteria Not reported Not funded

aThe other governorates are not specified

b UOSSM Union of Medical Care and Relief Organizations

c Violation Documentation Centre (VDC), Syrian Center for Statistics and Research (CSR-SY), Syrian Network for Human Rights (SNHR), and Syria Shuhada website (SS)

d Unfunded, the study was self-funded. This research was supported by Damascus University

e first published online in 2019, hence captured in this dataset

f The governorate is not specified