Table 3.
Univariate and multivariate logistic regression model analyses of prolonged LOS following primary THA with an ERAS program
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age (years) | 1.598 (1.177–2.019) | 0.019 | 2.315 (1.490–3.140) | 0.042 |
| Sex (%) | 0.765 (0.589–0.941) | 0.163 | 0.305 (0.256–0.354) | 0.039 |
| BMI (kg/m2) | 1.152 (0.973–1.363) | 0.105 | NA | |
| Harris score | 0.995 (0.978–1.013) | 0.594 | NA | |
| Hip deformities (%) | 0.297 (0.139–0.637) | 0.002 | 0.296 (0.098–0.894) | 0.031 |
| Hip joint mobility (°) | 1.625 (1.013–2.237) | < 0.001 | NA | |
| Preoperative VAS | 1.214 (1.035–1.425) | 0.017 | NA | |
| Preoperative Hb (g/L) | 0.974 (0.956–0.991) | 0.003 | NA | |
| Preoperative ALB (g/L) | 1.018 (0.963–1.075) | 0.53 | NA | |
| ASA (%) | 1.432 (0.877–2.338) | 0.151 | NA | |
| Operation time (min) | 1.014 (0.997–1.030) | 0.101 | NA | |
| Anesthesia time (min) | 1.018 (1.001–1.034) | 0.032 | NA | |
| Intraoperative infusion volume (ml) | 2.032 (1.709–2.355) | < 0.001 | 1.798 (1.645–1.951) | 0.028 |
| Intraoperative blood loss (ml) | 1.305 (1.185–1.425) | < 0.001 | 1.135 (1.068–1.202) | 0.008 |
| Out of bed activities time (h) | 1.151 (1.074–1.233) | 0.028 | NA | |
| Postoperative infusion volume (ml) | 1.007 (1.001–1.012) | 0.013 | NA | |
| Total infusion volume on the day of surgery (ml) | 1.004 (1.002–1.007) | 0.001 | NA | |
| VAS score on the day of surgery | 1.540 (1.062–2.232) | 0.023 | NA | |
| Day 1 after surgery VAS score | 1.512 (1.138–2.009) | 0.004 | NA | |
| POD Hb (g/L) | 0.951 (0.928–0.975) | < 0.001 | 0.955 (0.924- 0.987) | 0.006 |
| POD ALB (g/L) | 0.548 (0.481–0.615) | < 0.001 | 0.689 (0.656–0.722) | 0.026 |
| POD CRP (mg/L) | 0.971 (0.917–1.029) | 0.316 | NA | |
| POD IL 6 (pg/ml) | 1.485 (1.268–1.739) | < 0.001 | 1.312 (1.063- 1.620) | 0.011 |
| POD total blood loss 1 day after surgery (ml) | 1.002 (0.997–1.007) | 0.424 | NA | |
| POD Hb change rate (%) | 1.077 (1.038–1.118) | < 0.001 | NA | |
LOS > 48 h group; THA: total hip arthroplasty; ERAS: enhanced recovery after surgery; BMI, body mass index; VAS: visual analogue score; Hb: hemoglobin; ALB: albumin; ASA: American Society of Anesthesiologists; CRP: C-reactive protein; IL-6: interleukin-6; POD: one day after surgery. OR: odds ratio; CI, confidence interval; NA, not available
POD Hb change = (Preoperative Hb − POD Hb)/Preoperative Hb * 100%