Fig. 3.

STAT3 inhibition rescues the behavioral deficits of 5XE4 mouse model of AD. The cognitive function in experimental mice was assessed by measuring A exploratory preference in novel object recognition test, B exploratory preference in novel object location task, C novel arm entries in Y-maze test, D weight burrowed in burrowing test. Data is presented as mean ± SEM, #,*p < 0.05, #- as compared to veh + WT, *- as compared to veh + 5XE4, n = 9–10 in each group, veh- vehicle, WT- wild-type, 5XE4- 5XFAD/APOE4