Table 2.
Epidemiology and laboratory parameters of ulcerative colitis patients, stratified by disease activity
| Parameter | UC remission (N = 73) | UC active (N = 172) | P value |
|---|---|---|---|
| Age (years) | 47 (37–57) | 50 (38–61) | 0.331 |
| Sex: male | 32 (43.8) | 97 (56.4) | 0.072 |
| BMI (kg/m2) | 20.6 (18.8–21.7) | 19.3 (18.3–20.8) | 0.001 |
| Smoking: yes | 10 (13.7) | 29 (16.9) | 0.536 |
| Drinking: yes | 7 (9.6) | 15 (8.7) | 0.828 |
| Duration of disease (years) | 2.0 (0.7–4.3) | 1.1 (0.3–3.8) | 0.042 |
| Neutrophil (109/L) | 3.3 (2.7–4.4) | 4.6 (3.4–7.2) | < 0.001 |
| Monocyte (109/L) | 0.4 (0.4–0.6) | 0.7 (0.5–0.9) | < 0.001 |
| Lymphocyte (109/L) | 1.7 (1.5–2.2) | 1.8 (1.3–2.2) | 0.428 |
| Hb (g/dL) | 12.8 (12.0–13.5) | 11.9 (10.4–13.2) | < 0.001 |
| RDW (%) | 13.2 (12.7–13.9) | 13.3 (12.7–14.3) | 0.635 |
| Platelet (109/L) | 235 (201–270) | 281 (214–376) | < 0.001 |
| PT (s) | 13.4 (12.9–13.7) | 13.7 (13.1–14.6) | < 0.001 |
| INR | 1.0 (1.0–1.1) | 1.1 (1.0–1.1) | < 0.001 |
| Fibrinogen (g/L) | 2.7 (2.3–3.2) | 4.0 (3.0–5.0) | < 0.001 |
| CRP (mg/L) | 3.0 (1.5–3.2) | 12.8 (3.8–32.8) | < 0.001 |
| ESR (mm/h) | 6 (2–15) | 21 (11–37) | < 0.001 |
| NLR | 1.8 (1.3–2.7) | 2.8 (1.9–4.2) | < 0.001 |
| PLR | 130.0 (100.0–174.1) | 166.4 (121.6–222.5) | < 0.001 |
| LMR | 4.2 (3.4–5.1) | 2.7 (1.8–3.5) | < 0.001 |
Values are expressed as n (%) or median (IQR). UC ulcerative colitis; BMI body mass index; Hb hemoglobin; RDW red cell distribution width; PT prothrombin time; INR international normalized ratio; CRP C-reactive protein; ESR erythrocyte sedimentation rate; NLR neutrophil to lymphocyte ratio; PLR platelet to lymphocyte ratio; LMR lymphocyte to monocyte ratio