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. 2021 Dec 13;219(1):e20211539. doi: 10.1084/jem.20211539

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© 2021 Li et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 4. — TBK1 recruitment to STING induces inflammatory cytokines in DNase II^−/− mouse paws. (A–C) Quantitative RT-PCR analysis of inflammatory cytokine levels in paws from 8-mo-old male mice of the indicated genotypes (mean ± SD, n = 6–8 per genotype). Each dot represents a mouse. Statistical analysis was done using a two-tailed, unpaired Student’s test. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. Results are representative of four independent experiments. Ct, cycle threshold.