Table 1.
Demographic and hematological characteristics of patients with “Good syndrome”.
| UPN # | AGE (years) | Gender (M/F) | Good syndrome | PRCA | LGL | WBC/neutrophil count (×109/L) | Platelet count (×109/L) | Hb (g/dL) | Retic count (×109/L) | IgG (mg/dL) | IgM (mg/dL) | IgA (mg/dL) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 85 | M | Classic | Yes | Yes | 7.13/2.3 | 151 | 8.5 | 0.03 | 532 | 11 | 47 |
| 2 | 25 | M | Classic | Yes | Yes | 6.76/5.41 | 261 | 4.7 | 0.008 | <500 | 118 | 139 |
| 3 | 54 | M | Classic | Yes | Yes | 14.9/1.49 | 282 | 11.7 | 0.008 | <500 | 77 | 60 |
| 4 | 54 | M | Classic | Yes | No | 0.15/0 | 12 | 8.5 | <0.4 % a | 590 | 39 | 38 |
| 5 | 63 | F | Classic | Yes | No | 4.96/3.76 | 82 | 7.6 | 0.019 | 541 | 7 | 5 |
| 6 | 60 | M | Classic | No | No | 1.78/0.62 | 240 | 8.5 | NA | 487 | 35 | 30 |
| 7 | 62 | F | Classic | Yes | No | 18.5/13.96 | 409 | 15.5 | <0.4% a | 285 | <4 | 25 |
| 8 | 58 | F | Classic | No | No | 17.70/16.67 | 213 | 12.6 | NA | 240 | 50 | 133 |
| 9 | 51 | F | Classic | No | No | 6.06/3.3 | 218 | 14.03 | NA | 51 | <5 | <8 |
| 10 | 71 | F | Classic | No | No | 11.58/4.17 | 312 | 12.6 | NA | 69 | 4 | 7 |
| 11 | 83 | F | Classic | Yes | No | 2.92/1.87 | 165 | 7.5 | 0.029 | 50 | <4 | 10 |
| 12 | 65 | M | Classic | No | No | 7.16/4.18 | 260 | 15.2 | 0.126 | 247 | 184 | <7 |
| 13 | 40 | F | Classic | No | No | 9.32/6.79 | 265 | 15 | NA | NA | NA | NA |
| 14 | 47 | M | Classic | No | No | 4.1/3.1 | 178 | 16.9 | NA | 470 | NA | NA |
| 15 | 87 | F | Classic | No | No | 11.1/9.1 b | 555 | 12.8 | NA | 648 | 23 | 83 |
| 16 | 60 | F | Classic | No | No | 3.1 /1.0 | 287 | 14.9 | 0.039 | 704 | 51 | 141 |
| 17 | 46 | F | Probable | NA | NA | NA | NA | NA | NA | 907 | 42 | 108 |
| 18 | 65 | M | Classic | No | No | 11.38/9.41 | 155 | 11 | NA | 420 | 48 | 105 |
| 19 | 72 | M | Probable | No | No | 8.72/7.05 | 337 | 13.1 | NA | 860 | 78 | <7 |
| 20 | 42 | F | Classic | No | No | 5.23/4.41 | 191 | 11.9 | 0.135 | <500 | NA | NA |
| 21 | 56 | M | Probable | No | No | 3.42/2.2 | 391 | 8.8 | 0.045 | 1800 c | 6 | 17 |
| 22 | 52 | F | Classic | No | No | 3.98/2.33 | 271 | 12 | 0.036 | <500 | 161 | 409 |
| 23 | 84 | F | Classic | No | No | 10.1/7.3 | 208 | 14.4 | NA | 694 | NA | NA |
| 24 | 31 | F | Probable | No | No | 5.72/3.06 | 248 | 14 | NA | NA | NA | 26 |
All findings were registered at the time of Good syndrome onset.
Abnormal values are highlighted in bold. Normal ranges were considered according to the followings: WBC, 3.70–11.00 ×109/L; neutrophil count, 1.45–7.50 ×109/L; platelet count, 150–400 ×109/L; Hb, 11.5–15.5 g/dL; reticulocytes count, 0.0180–0.1000 M/µL; IgG, 717–1411 mg/dL; IgA, 78–391 mg/dL; IgM, 53–334 mg/dL.
M male, F female, Hb hemoglobin, Ig immunoglobulin, LGL large granular lymphocytic leukemia, retic reticulocytes, PRCA pure red cell aplasia, TCR T-cell receptor rearrangement, WBC white blood cell, MGUS monoclononal gammopathy of undertermined significance.
Patients with absolute reticulocytes counts not reported due to very low counts below analyzer linearity.
Patient with essential thrombocythemia (ET).
Patient with monoclonal gammopathy of undetermined significance (MGUS IgGk).