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. 2021 Dec 15;41(50):10365–10381. doi: 10.1523/JNEUROSCI.1475-21.2021

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Figure 1. — 17αE2 treatment protects against dendritic damage in HIV-1 transgenic rats. A, Golgi–Cox staining of dendritic arborization and dendritic spine density in hippocampi of male HIV-1 Tg rats compared with F344 control (Ctrl) rats. Dendritic shafts within red boxes are enlarged in the bottom panel showing the distribution and type of spines. B–E, Quantification of dendritic length (B), density of stubby dendritic spines (C), density of mushroom dendritic spines (D), and density of long/thin dendritic spines (E). N shows the number of neurons analyzed from at least 30 images from different hippocampus regions from five animals in each group.