Table 4.
Number and percentage of significant voxels during fear extinction learning (n = 79, TFCE-corrected p < 0.05) within each mask, and MNI coordinates of local maxima
L amygdala (p > 0.01) (1452 voxels) | R amygdala (p > 0.01) (1623 voxels) | L amygdala (p > 0.25) (432 voxels) | R amygdala (p > 0.25) (492 voxels) | L amygdala (p > 0.50) (240 voxels) | R amygdala (p > 0.50) (280 voxels) | |
---|---|---|---|---|---|---|
CS+ > CS– | ||||||
2 mm | 15 (1.0%) | 0 | 0 | 0 | 0 | 0 |
[−28, −14, −10]a | ||||||
5 (0.3%) | ||||||
[−28, 6, −18]b | ||||||
1 (0.1%) | ||||||
[−18, −2, −10]c | ||||||
5 mm | 22 (1.5%) | 0 | 0 | 0 | 0 | 0 |
[−30, 6, −14]d | ||||||
14 (1.0%) | ||||||
[−30, −16, −10]e | ||||||
8 mm | 29 (2.0%) | 0 | 0 | 0 | 0 | 0 |
[−32, 6, −16]f | ||||||
4 (0.3%) | ||||||
[−30, −16, −10]e | ||||||
CS– > CS+ | ||||||
2 mm | 193 (13.3%) | 157 (9.7%) | 137 (31.7%) | 77 (15.7%) | 106 (44.2%) | 55 (19.6%) |
[−18, −12, −22]g | [22, −10, −16]h | [−18, −8, −20]i | [22, −10, −16]h | [−16, −6, −20]j | [22, −6, −20]k | |
5 mm | 215 (14.8%) | 147 (9.1%) | 136 (31.5%) | 67 (13.6%) | 105 (43.8%) | 50 (17.9%) |
[−18, −12, −22]g | [22, −8, −16]l | [−16, −8, −20]m | [22, −8, −16]l | [−28, −4, −20]n | [22, −8, −16]l | |
8 mm | 197 (13.6%) | 132 (8.1%) | 140 (32.4%) | 61 (12.4%) | 100 (41.7%) | 42 (15.0%) |
[−18, −12, −22]g | [20, −8, −20]o | [−20, −6, −22]p | [20, −8, −20]o | [−20, −6, −22]p | [20, −6, −20]k | |
Face > house | ||||||
2 mm | 81 (5.6%) | 21 (1.3%) | 114 (26.4%) | 28 (5.7%) | 103 (42.9%) | 23 (8.2%) |
[−18, −8, −14]q | [28, −16, −12]r | [−18, −8, −14]q | [24, 2, −18]s | [−18, −8, −14]q | [24, 2, −18]s | |
3 (0.1%) | 3 (0.6%) | |||||
[24, 2, −18]s | [26, −14, −12]v | |||||
1 (0.1%) | ||||||
[20, −2, −14]t | ||||||
1 (0.1%) | ||||||
[12, −4, −10]u | ||||||
5 mm | 69 (4.8%) | 96 (5.9%) | 112 (25.9%) | 91 (18.5%) | 105 (43.8%) | 67 (23.9%) |
[−20, −8, −14]w | [30, −18, −10]x | [−20, −8, −14]w | [24, 2, −18]s | [−20, −8, −14]w | [24, 2, −18]s | |
8 mm | 70 (4.8%) | 70 (4.3%) | 128 (29.6%) | 100 (20.3%) | 126 (52.5%) | 77 (27.5%) |
[−20, −8, −14]w | [20, −2, −10]y | [−20, −8, −14]w | [20, −2, −12]bb | [−20, −8, −14]w | [20, −2, −12]bb | |
41 (2.5%) | ||||||
[30, −16, −12]z | ||||||
1 (0.1%) | ||||||
[24, −8, −16]aa | ||||||
House > face | ||||||
2 mm | 0 | 0 | 0 | 0 | 0 | 0 |
5 mm | 0 | 0 | 0 | 0 | 0 | 0 |
8 mm | 0 | 0 | 0 | 0 | 0 | 0 |
Labels associated with local maxima are based on the Harvard-Oxford probabilistic atlas. Some of the peak coordinates fall just outside the amygdala, because - because of resampling - the anatomical mask at the lowest threshold (p > 0.01) is slightly larger than the atlas indicates. R, Right; L, left.
a71% L cerebral white matter, 17% L putamen, 6% L amygdala, 3% L hippocampus, 1% L pallidum.
b78% L cerebral cortex, 2% L amygdala.
c51% L cerebral white matter, 32% L cerebral cortex, 7% L amygdala, 7% L pallidum.
d77% L cerebral cortex, 20% L cerebral white matter.
e74% L cerebral white matter, 19% L putamen, 4% L hippocampus, 1% L amygdala.
f82% L cerebral cortex, 8% L cerebral white matter, 1% L amygdala.
g87% L hippocampus, 9% L cerebral cortex, 3% L cerebral white matter, 1% L amygdala.
h47% R amygdala, 34% R hippocampus.
i55% L hippocampus, 44% L amygdala.
j63% L amygdala, 33% L hippocampus, 3% L cerebral cortex.
k74% R amygdala, 25% R hippocampus.
l77% R amygdala, 14% R hippocampus.
m58%L hippocampus, 35% L amygdala, 6% L cerebral cortex.
n96% L amygdala, 3% L hippocampus, 1% L cerebral white matter, 1% L cerebral cortex.
o64% R hippocampus, 34% R amygdala.
p60% L amygdala, 40% L hippocampus.
q92% L amygdala, 4% L cerebral white matter, 1% L hippocampus.
r40% R hippocampus, 21% R cerebral white matter, 11% R amygdala,.
s67% R amygdala, 21% R cerebral cortex, 0% Right cerebral white matter.
t72% R amygdala, 17% R cerebral cortex, 2% Right cerebral white matter.
u64% R cerebral white matter, 9% Right pallidum, 3% R cerebral cortex.
v31% R amygdala, 20% R cerebral white matter, 17% R hippocampus.
w96% L amygdala, 1% L cerebral white matter, 1% L hippocampus.
x65% R cerebral white matter, 24% R hippocampus, 2% R amygdala.
y45% R cerebral white matter, 25% R cerebral cortex, 25% R amygdala, 4% R pallidum.
z41% R cerebral white matter, 39% R hippocampus, 6% R amygdala.
aa76% R amygdala, 12% R hippocampus.
bb50% R amygdala, 30% R cerebral cortex, 13% R cerebral white matter, 2% R pallidum.