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. 2021 May 11;224(12):2053–2063. doi: 10.1093/infdis/jiab253

Table 2.

Twelve HIV AA Variants Significantly Associated With Varying Numbers of Host SNPs

HIV AA Variant Lowest P Value Number of Associated Host SNPs Region of Associated Host SNPs
GAG242N 1.22 × 10–79 512 chr6:29818568–32626272; chr15:50785016
GAG302K 1.35 × 10–16 8 chr6:30993440–31326410
GAG357S 3.17 × 10–16 48 chr6:31005726–31812038
GAG397R 1.13 × 10–32 186 chr6:29607476–30222020
GAG403K 2.78 × 10–19 4 chr6:29830074–29924779
POL432R (RT277R) 6.26 × 10–39 134 chr6:29611885–30711805
POL837I (INT122I) 1.85 × 10–11 1 chr6:31316609
NEF071K 1.38 × 10–31 150 chr6:30861729–31879158
NEF092R 4.70 × 10–19 8 chr6:29785827–30026290
NEF102H 8.79 × 10–16 1 chr6:29785827–30026290
NEF105R 9.38 × 10–12 3 chr6:31242649–31245821
NEF135F 6.36 × 10–21 8 ch6:29735280–29992261

The information on host and viral variant location in the genome together with the lowest P value are reported.

Abbreviations: AA, amino acid; HIV, human immunodeficiency virus; INT, integrase; RT, reverse transcriptase; SNP, single nucleotide polymorphism.