Clearance by human liver microsomes (HLM) of oxetanes vs. ketones.
| Oxetane | HLM Clint (μL min−1 mg−1) | Ketone | HLM Clint (μL min−1 mg−1) |
|---|---|---|---|
|
22.9 |
|
18 |
|
<7 |
|
<7 |
|
80 |
|
77.4 |
|
7.5 |
|
75 |
|
8.5 |
|
<7 |
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