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. 2021 Dec 15;9(3):e01330-21. doi: 10.1128/Spectrum.01330-21

TABLE 1.

Baseline characteristics of the study cohort on sex, age, BMI, smoking, alcohol use, previous test result, and comorbidities stratified by seropositivitya

Full cohort Seronegative Seropositive P
n 316,033 2,519
Age (yrs) (median [IQR]) 53 [39-64]) 55 [42-64] 0.041
Male (%) 113,412 (422) 1,012 (40.2) <0.001
Body mass index (median [IQR]) 25.4 [22.8, 28.7] 25.5 [23, 29] 0.115
Ever smoker (%) 168,024 (53.2) 1,375 (54.6) 0.161
Alcohol use (%) 36,747 (12.9) 302 (13.5) 0.443
Comorbidities (%)
    Myocardial infarction 6562 (2.1) 59 (2.3) 0.389
    Stroke 9067 (2.9) 91 (3.6) 0.030
    Hypertension 82215 (26.0) 711 (28.2) 0.013
    Diabetes 17528 (5.5) 165 (6.6) 0.032
    Cancer 23250 (7.4) 185 (7.3) 1.000
    Rheumatoid arthritis 19309 (6.1) 176 (7.0) 0.074
    COPD 13872 (4.4) 150 (6.0) <0.001
    Asthma 43996 (13.9) 375 (14.9) 0.172
    Other chronic disease 56134 (17.8) 456 (18.1) 0.675
Work type
    Not working 123,959 (39.2) 947 (37.6)
    Office work 83,401 (43.4) 538 (34.2)
    Tradesman 20,653 (10.8) 154 (9.8)
    School/other education 23,773 (12.4) 199 (12.7)
    Shop work 9,103 (4.7) 78 (5.0)
    Nursing home 5,768 (3.0) 57 (3.6)
    Healthcare sector 21,863 (11.4) 287 (18.3)
    Home care 3,827 (2.0) 52 (3.3.)
    Other 44,755 (23.3) 370 (23.5)
Exposed to SARS-CoV-2 infected person
    Yes 32,099 (10.2) 713 (28.3)
    No 212,966 (67.4) 1,208 (48.0)
    Do not know 70,968 (22.5) 598 (23.7) <0.001

aAlcohol use: Reporting >7 units of alcohol a week for females or >14 units of alcohol for male. The cohort enncompasses students, stay-at-home persons, out of job, long-term sick leave, retired, and persons on parental leave. Occupations are counted as the percentage of seropositive among those working. Each participant can have more than one type of occupation; thus, the percentage sums up to more than 100.