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Reactivities of (putative) GL-specific MAbs with NR virus variants in IPMA
| Escape mutant | Reactivity
|
|||||
|---|---|---|---|---|---|---|
| Nonneutralizing anti-GL MAbs
|
Neutralizing anti-GL MAbs
|
|||||
| E3/c16 | E3/d10 | E6/B8 | E6/A3 | E7/d15-c1 | E7/d15-c9 | |
| NR E6/A3, plaque no. 5 | + | + | + | − | + | + |
| NR E7/d15-c1, plaque no. 7 | + | + | + | + | − | + |
| NR E7/d15-c9,a plaque no. 4 | + | + | + | + | + | + |
Although stainable by the MAb used for selection, this NR was less well neutralized by MAb E7/d15-c9 than the parental virus.
