Model‐adjusted changes in blood pressure (mm Hg) measured by ambulatory blood pressure monitoring (efficacy population, last‐observation‐carried‐forward) comparing high‐dose monotherapy groups with the combined group who received either extended‐release carvedilol/lisonopril (Carv CR/Lis) 80/10 mg, 80/20 mg, 80/40 mg, 20/40 mg, and 40/40 mg. C indicates carvedilol; L, lisinopril; NS, not significant.