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. 2009 Jun 23;11(7):376–382. doi: 10.1111/j.1751-7176.2009.00138.x

Table III.

 Factors Influencing Persistence With Antihypertensive Medication Regimens and Discontinuation of Therapy

Factor Finding
Age Older patients more persistent than younger patients
Sex Women usually more persistent than men
Initial monotherapy Persistence highest with angiotensin receptor blockers, lowest with diuretics
Comorbidity Discontinuation rates higher with higher comorbidity index
Adverse effects Occurrence of adverse effects increases discontinuation
Prescription coverage Discontinuation rates lower with drug coverage