Table II.
Mean± SD, mm Hg | Baseline | Olmesartan Morning Dose | Olmesartan Night Dose | P Valueb |
---|---|---|---|---|
24‐hour SBP | 138.48±9.27 | 124.80±7.14a | 124.09±6.89a | .86 |
24‐hour DBP | 87.47±8.36 | 78.91±9.01a | 77.4±6.97a | .36 |
24‐hour MBP | 104.3±7.99 | 93.52±6.56a | 92.96±6.20a | .83 |
24‐hour HR | 82.16±10.21 | 76.57±10.44a | 76.49±10.39a | .99 |
Day SBP | 142.16±11.73 | 128.65±8.47a | 129.52±8.19a | .83 |
Day DBP | 89.53±9.02 | 81.35±8.17a | 81.06±7.42a | .95 |
Day MBP | 106.97±9.26 | 96.46±6.89a | 97.22±6.62a | .73 |
Day HR | 85.25±10.95 | 79.39±10.90a | 79.58±11.11a | .97 |
Night SBP | 124.26±8.38 | 112.39±9.61a | 108.07±9.11a | .007 |
Night DBP | 80.82±7.8 | 73.97±12.34a | 71.04±7.71a | .069 |
Night MBP | 95.32±6.96 | 86.77±9.39a | 83.35±7.75a | .012 |
Day HR | 72.12±9.99 | 67.78±10.80a | 66.90±10.60a | .47 |
Abbreviations: ABPM, ambulatory blood pressure monitoring; DBP, diastolic blood pressure; HR, heart rate; MBP, mean blood pressure; SBP, systolic blood pressure; SD, standard deviation. a P<.0001 compared with baseline. bMorning vs nighttime dosing.