Table.
Baseline Characteristics
| Depression n=21 | Nondepression n=21 | P Value | |
|---|---|---|---|
| Age, y | 73.9±9.2 | 70.1±8.7 | NS |
| Male, % | 38 | 38 | NS |
| Body mass index, kg/m2 | 23.8±3.2 | 24.2±3.0 | NS |
| Current drinking, No. (%) | 6 (29) | 6 (29) | NS |
| Current smoking, No. (%) | 5 (24) | 2 (10) | NS |
| Duration of hypertension, y | 9.0 (7.0–17.5) | 10.0 (3.0–16.5) | NS |
| Duration of hypertensive therapy, y | 7.0 (3.0–14.5) | 7.0 (0.5–15.0) | NS |
| Diabetes, No. (%) | 5 (24) | 2 (10) | NS |
| Hyperlipidemia, No. (%) | 6 (29) | 6 (29) | NS |
| ARB, No. (%) | 6 (29) | 5 (24) | NS |
| ACE inhibitor, No. (%) | 8 (38) | 14 (67) | NS |
| Calcium channel blocker, No. (%) | 18 (86) | 17 (81) | NS |
| β‐Blocker, No. (%) | 4 (19) | 1 (5) | NS |
| Diuretics, No. (%) | 5 (24) | 2 (10) | NS |
| α‐Blocker, No. (%) | 4 (19) | 3 (14) | NS |
| Brain natriuretic peptide, pg/mL | 37.7 (22.1–60.1) | 23.3 (16.9–31.1) | <.05 |
| Serum creatinine, mg/dL | 0.7 ± 0.2 | 0.8 ± 0.2 | NS |
| Estimated GFR, mL/min/1.73 m2 | 91.5±21.9 | 79.7±14.6 | NS |
| Urinary albumin/creatinine ratio, mg/gCr | 30.9 (10.1–143.2) | 25.4 (11.5–83.7) | NS |
| Clinic systolic blood pressure, mm Hg | 164±27 | 162±14 | NS |
| Clinic diastolic blood pressure, mm Hg | 84±13 | 82±12 | NS |
| Clinic pulse rate, bpm | 76±11 | 77±15 | NS |
| Home systolic blood pressure, mm Hg | 150±17 | 150±11 | NS |
| Home diastolic blood pressure, mm Hg | 78±11 | 76±9 | NS |
| Home pulse rate, bpm | 70±8 | 70±10 | NS |
Data are shown as the No. (percentage) or mean ± standard deviation. Duration of hypertension, duration of hypertensive therapy, brain natriuretic peptide and urinary albumin ratio are the median values (25% value–75% value).
Abbreviations: ACE, angiotensin‐converting enzyme; ARB, angiotensin receptor blockers; bpm, beats per minute; GFR, glomerular filtration rate; NS, not significant.