Table II.
Clinical and Hemodynamic Data and QTd
| Parameter (×±1 SD) | Intervention Group | Control Group | P Value End Intervention vs Control Group | ||||
|---|---|---|---|---|---|---|---|
| Baseline | 6 Months | P Value Baseline vs End | Baseline | 6 Months | P Value Baseline vs End | ||
| Body weight, kg | 82±8 | 79±7 | <.0001 | 81±9 | 81±9 | NS | >.0001 |
| Calories, kcal | 2621±387 | 1669±147 | <.0001 | 2618±389 | 2706±401 | NS | >.0001 |
| SBP, mm Hg | 152±5 | 145±5 | <.0001 | 152±4 | 150±5 | >.02 | >.0001 |
| DBP, mm Hg | 88±6 | 85±5 | >.0001 | 88±5 | 87±5 | NS | >.0001 |
| Heart rate, beats/min | 74±7 | 72±6 | NS | 73±6 | 72±7 | NS | NS |
| NYHA class | 1.8±0.4 | 1.4±0.3 | <.005 | 1.8±0.4 | 1.8±0.5 | NS | >.0001 |
| NT‐proBNP, pg/mL | 719±165 | 526±126 | <.0001 | 717±141 | 741±189 | NS | >.0001 |
| GFR, mL/min/m2 | 77.6±9.6 | 82.5±8.6 | >.0001 | 77.6±9.3 | 76.0±9.1 | NS | >.0001 |
| Ergometry | |||||||
| Exercise duration, min | 7±1 | 9±2 | >.0001 | 7±1 | 7±1 | NS | >.0001 |
| Maximal exercise capacity, W | 90±12 | 120±24 | >.0001 | 92±15 | 97±21 | >.09 | >.0001 |
| Electrocardiography | |||||||
| QTd, ms | 46±10 | 46±10 | NS | 47±9 | 48±9 | NS | NS |
Abbreviations: DBP, diastolic blood pressure; GFR, glomerular filtration rate; End, end of the observational period; NS, not significant; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; NYHA, New York Heart Association; QTd, QT dispersion; SBP, systolic blood pressure; SD, standard deviation.