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. 2010 Jan 19;12(5):374–379. doi: 10.1111/j.1751-7176.2009.00259.x

Table II.

 Quantitative Changes of MS Criteria and Different Biochemical Parameters According to the Presence of MS

N=642 MS (n=171; 26.7%) No MS (n=471; 73.3%) P MS P No MS P MS vs No MS
Body mass index, kg/m2 Baseline 28.9±3.9 26.2±2.9 NS NS <.001
Study end 28.8±3.8 26.3±3.0
Waist circumference, cm Baseline 100.8±9.3 95.3±8.7 NS NS .006
Study end 99.4±9.3 95.4±9.1
Systolic blood pressure, mm Hg Baseline 138.6±17.6 124.4±18.4 <.001 NS <.001
Study end 129.9±17.6 124.7±18.9
Diastolic blood pressure, mm Hg Baseline 86.4±9.5 80.3±11.5 NS NS <.001
Study end 82.8±10.1 79.5±11.0
Pulse pressure, mm Hg Baseline 52.2±6.3 44.1±5.1 .01 NS <.001
Study end 47.1±5.2 45.2±5.3
Total cholesterol, mg/dL Baseline 187.4±40.1 182.8±42.0 <.001 <.001 NS
Study end 167.7±34.6 166.7±30.8
LDL cholesterol, mg/dL Baseline 119.4±35.5 116.0±35.6 <.001 <.001 NS
Study end 99.5±25.1 99.1±25.5
NEFA, mg/dL Baseline 213.8±69.3 148.1±50.4 NS NS <.001
Study end 201.6±93.3 152.5±57.0
HDL cholesterol, mg/dL Baseline 35.6±8.7 43.7±12 <.001 <.001 <.001
Study end 38.5±9.4 45.3±12.2
VLDL cholesterol, mg/dL Baseline 32.7±26.8 22.6±19.9 <.001 <.001 <.001
Study end 27.7±18.7 21.4±11.4
Triglycerides, mg/dL Baseline 176.8±90.9 111.9±46.1 <.001 NS <.001
Study end 149.9±73.2 107.7±44.6
Apolipoprotein B, mg/dL Baseline 107.4±26.6 93.7±26.2 <.001 <.001 <.001
Study end 97.0±27.1 87.0±29.9
TG/HDL cholesterol Baseline 5.3±3.5 2.8±1.6 <.001 NS <.001
Study end 4.3±3.2 2.6±1.6
Fasting glucose, mg/dL Baseline 125.6±37.0 102.9±22.6 <.001 NS <.001
Study end 120.1±42.2 103.2±19.5
HbA1c, % Baseline 7.7±2.4 5.6±0.3 NS NS .025
Study end 7.7±2.7 5.6±0.4
HOMA index Baseline 4.9±2.9 2.9±1.9 .05 NS .059
Study end 3.9±3.1 3.1±2.8

Abbreviations: HbA1c, glycated hemoglobin A1c; HDL, high‐density lipoprotein; HOMA, homeostasis model assessment; LDL, low‐density lipoprotein; MS, metabolic syndrome; NEFA, nonesterified fatty acid; NS, not significant; P MS, P value between baseline and study end in patients with MS; P MS vs No MS, P value between baseline values in patients with and without MS; P No MS, P value between baseline and study end in patients without MS; TG, triglycerides; VLDL, very low‐density lipoprotein.