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Targets of angry fat. Activation of the RAAS in adipose tissue is associated with an increase in production of cytokines that communicate the health of the adipose tissue to the nonadipose organs throughout the body. PAI‐1 = plasminogen activator inhibitor 1; PPARs = peroxisome proliferators‐activated receptors; RXR = retinoid × receptor; LVH = left ventricular hypertrophy.
