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. Author manuscript; available in PMC: 2021 Dec 15.
Published in final edited form as: Virology. 2021 May 10;560:17–33. doi: 10.1016/j.virol.2021.04.013

Fig. 6. Inhibition of ZIKV infection of various cells types.

Fig. 6.

Fig. 6.

Fig. 6.

Fig. 6.

Fig. 6.

Fig. 6.

ZIKV replicon was incubated with 1 or 10 μg/ml of ZKA64, sTIM1dMLDR801, or NCFcR801, or control medium for 1 hour at room temperature. U87 (A), NHDF (B), CCD1064sk (C), FRPE (D), dendritic cells (E), and C6/36 cells were infected with the incubated virus for 2 hours, and the infections were analyzed by flow cytometry 24 hours post-infection. The results shown are averages and standard deviations of the triplicate experiment. Significance was first calculated by comparing infections of each cell type without Gas6 to those with Gas6, using a two-sample two-sided unpaired student t-test. Significance was next calculated by comparing infection of each cell types without blocking reagents in the absence of Gas6 to those with blocking reagents in the absence of Gas6, using a two-sample two-sided unpaired student t-test. Significance was then calculated by comparing infection of each cell types without blocking reagents in the presence of Gas6 to those with blocking reagents in the presence of Gas6, using a two-sample two-sided unpaired student t-test (*, p<0.05; **, p<0.01).