. 2021 Nov 23;84(3):1039–1055. doi: 10.3233/JAD-215085

Table 8.

Determinants of attention/speed at the end of study: LnMap_Search_2, placebo group^*

Variable (n = 82–112)	Pearson correlation		Multiple regression^#
			Model 1		Model 2		Model 3		Model 4
	β	p	β	p	β	p	β	p	β	p
LntHcy_1	–0.39	0.000		NS		NS		NS		NS
LnSi_1	–0.02	0.858	0.27	0.010				0.25	0.021
			0.25^$	0.022 ^$			0.22^$	0.048 ^$
LnCu_1	–0.10	0.347	–0.25	0.033	–0.22	0.072
			–0.22^$	0.061 ^$
LnBrain Volume_1	0.40	0.000	0.09^$	0.490^$			0.16^$	0.231^$
LnAtrophy_rate	–0.30	0.011	–0.15	0.194	–0.13	0.255	–0.12	0.300	–0.14	0.159
LnMap_Search_1	0.65	0.000	0.42	0.000	0.41	0.001	0.40	0.001	0.41	0.000
Age	–0.36	0.000	–0.25	0.048	–0.21	0.137	–0.24	0.065	–0.27	0.011
			F = 7.16,		F = 6.42,		F = 6.95,		F = 9.96,
			p = 0.000,		p = 0.000,		p = 0.000,		p = 0.000,
			Adjusted		Adjusted		Adjusted		Adjusted
			R² = 0.48		R² = 0.42		R² = 0.44		R² = 0.46

^*Ln, natural logarithm; _1, baseline; _2, end of study; NS, not significant. ^#Adjusted for LntHcy_1, LnCys_1, LnTaurine_1, age, and sex. ^$Adjusted for LnBrain_Volume_1.