TABLE 9.
Ruleb | No. of bands | Average
|
Laboratory A
|
Laboratory B
|
Laboratory C
|
Laboratory D (B. afzelii)
|
Laboratory D (B. garinii)
|
Laboratory E (no IgM OspC)
|
Laboratory F
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
% Sensc | % Specd | % Sens | % Spec | % Sens | % Spec | % Sens | % Spec | % Sens | % Spec | % Sens | % Spec | % Sens | % Spec | % Sens | % Spec | ||
1 | 2 | 68 | 91 | 85 | 92 | 59 | 95 | 73 | 78 | 55 | 99 | 53 | 99 | 81 | 91 | 73 | 80 |
3 | 29 | 100 | 45 | 100 | 25 | 100 | 33 | 99 | 19 | 100 | 11 | 100 | 34 | 99 | 38 | 99 | |
2 | 2 | 75 | 89 | 85 | 92 | 81 | 94 | 73 | 78 | 61 | 98 | 57 | 99 | 88 | 85 | 82 | 79 |
3 | 49 | 98 | 54 | 99 | 53 | 99 | 41 | 99 | 43 | 99 | 37 | 100 | 64 | 97 | 50 | 97 | |
3 | 2 | 87 | 72 | 92 | 73 | 87 | 88 | 96 | 44 | 75 | 92 | 72 | 89 | 95 | 70 | 95 | 47 |
3 | 69 | 92 | 76 | 95 | 66 | 98 | 71 | 82 | 57 | 99 | 50 | 99 | 84 | 91 | 81 | 80 | |
4 | 2 | 77 | 88 | 86 | 89 | 81 | 94 | 74 | 76 | 67 | 97 | 57 | 99 | 89 | 84 | 82 | 79 |
3 | 56 | 98 | 66 | 99 | 56 | 99 | 47 | 99 | 54 | 99 | 40 | 100 | 67 | 97 | 56 | 97 | |
5 | 2 | 87 | 72 | 93 | 71 | 88 | 88 | 96 | 46 | 80 | 92 | 74 | 89 | 95 | 69 | 95 | 47 |
3 | 71 | 92 | 80 | 94 | 67 | 98 | 73 | 81 | 62 | 98 | 51 | 99 | 85 | 91 | 81 | 80 | |
6 | 2 | 79 | 86 | 86 | 87 | 85 | 92 | 78 | 76 | 68 | 97 | 57 | 99 | 89 | 84 | 88 | 67 |
3 | 62 | 96 | 73 | 95 | 60 | 99 | 56 | 99 | 56 | 99 | 42 | 100 | 68 | 96 | 78 | 87 | |
7 | 2 | 90 | 70 | 93 | 69 | 91 | 86 | 96 | 44 | 83 | 92 | 74 | 89 | 95 | 69 | 97 | 39 |
3 | 74 | 90 | 82 | 92 | 69 | 98 | 77 | 81 | 62 | 98 | 57 | 99 | 85 | 91 | 88 | 69 | |
4 | 58 | 97 | 69 | 97 | 49 | 99 | 55 | 99 | 54 | 99 | 38 | 100 | 66 | 97 | 77 | 87 |
Examples of the “best” qualifying rules (70% sensitivity and 90% specificity) for each laboratory are given in boldface italic type.
Rules 1 and 3 were eliminated because they did not provide an adequate combination of sensitivity and specificity for all laboratories.
Sens, sensitivity was calculated by combining data for IgG and IgM.
Spec, specificity was calculated by combining data for potential cross-reactor and healthy individuals' sera.