Table 7. Prediction of class and accuracy, organ toxicity, oral acute toxicity and genetic toxicity endpoints of candidate compounds.
Sr. No | Compound name | Oral LD50 value (mg/Kg) | Predicted toxicity class | Prediction accuracy (%) | Hepato-toxicity | Proba-bility | Cytotoxicity | Proba-bility |
---|---|---|---|---|---|---|---|---|
1 | Enterodiol | 2950 | V | 69.26% | Inactive | 0.80 | Inactive | 0.93 |
2 | Aloin | 221 | III | 68.07% | Inactive | 0.85 | Inactive | 0.83 |
3 | Ononin | 3100 | V | 64.71% | Inactive | 0.83 | Inactive | 0.58 |
4 | RhinacanthinF | 4000 | V | 68.07% | inactive | 0.83 | Inactive | 0.95 |
5 | Rhazin | 300 | III | 68.07% | Inactive | 0.85 | Inactive | 0.69 |
6 | Alkannin beta, beta-dimethylacrylate | 1000 | IV | 72.9% | Inactive | 0.54 | Inactive | 0.88 |
7 | Aloesin | 832 | IV | 67.38% | Inactive | 0.80 | Inactive | 0.78 |
8 | Ancistrocladine | 450 | IV | 69.26% | inactive | 0.64 | Inactive | 0.51 |