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. 2021 Dec 15;16(12):e0261168. doi: 10.1371/journal.pone.0261168

Table 4. Univariate and multiple Cox analysis for in-hospital mortality of serum sodium quartiles groups.

Univariate Multivariate
HR 95%CI P HR 95%CI P
years 1.014 0.994–1.034 0.171
male 0.678 0.414–1.111 0.123
Hypertension 1.312 0.684–2.152 0.509
Diabetes 1.004 0.246–4.101 0.995
CAD 1.430 0.617–3.317 0.404
Smoking 0.768 0.474–1.243 0.282
Drinking 0.873 9,543–1.405 0.576
Stanford type A 4.503 2.048–9.899 <0.001 3.634 1.638–8.060 0.002
History of trauma 1.485 0.540–4.081 0.443
Surgical history 1.127 0.663–1.914 0.659
Heart rate 0.998 0.984–1.012 0.770
SBP 0.987 0.978–0.995 0.002
DBP 0.986 0.973–0.999 0.032
ALT 1.000 0.999–1.001 0.814
AST 1.000 1.000–1.000 0.996
Creatinine 1.002 1.000–1.003 0.044
Urea nitrogen 1.028 0.994–1.063 0.106
Serum glucose 1.067 1.018–1.117 0.007 1.077 1.025–1.132 0.003
α-HBDH 1.001 1.001–1.002 <0.001 1.001 1.001–1.002 <0.001
WBC count 1.029 0.973–1.088 0.312
Neutrophil count 1.032 0.975–1.093 0.274
lymphocyte count 0.754 0.462–1.228 0.256
Monocyte count 1.405 0.738–2.675 0.300
Serum sodium 1.074 1.035–1.116 <0.001 1.068 1.029–1.109 0.001
Serum potassium 0.999 0.983–1.015 0.889
Serum chloride 1.011 0.989–1.033 0.344
Serum calcium 0.255 0.073–0.899 0.034

CAD: coronary artery disease; SBP: systolic blood pressure; DBP, diastolic blood pressure; ALT: Alanine transaminase; AST: Aspartate transaminase; α-HBDH: alpha-hydroxybutyric dehydrogenase; WBC: white blood cell.

For numerical raw data, please see S1 Data.