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. 2021 Dec 15;16(12):e0261154. doi: 10.1371/journal.pone.0261154

Table 4. Factors associated with tobacco dependence among schizophrenic patients at Mettu Karl referral, Bedelle and Agaro hospitals, southwest Ethiopia, 2020 (N = 515).

Variable Category Tobacco use COR, 95% (CI) AOR, 95% (CI)
Not dependent N (%) Dependent N (%)
Sex Female 147 (84.5) 27 (15.5) Ref Ref
Male 253 (74.2) 88 (25.8) 1.89 (1.18,3.05) 2.19 (1.25,3.83)**
Occupational status Government employed 79 (76.9) 24 (23.3) Ref Ref
Self-employed 168 (90.8) 17 (9.2) 0.33 (0.17,0.66) 0.41 (0.17, 1.00)
Unemployed 153 (67.4) 74 (32.6) 1.59 (0.93,2.72) 2.09 (0.98, 4.49)
Frequency of admission None 146 (71.9) 57 (28.1) Ref Ref
1 124 (80.0) 31 (20.0) 0.79 (0.43,1.45) 1.32 (0.66, 2.65)
2 92 (81.4) 21 (18.6) 0.55 (0.29,1.03) 1.63 (0.66,4.01)
3 38 (86.4) 6 (13.6) 0.46 (0.19,1.12) 0.67 (0.23,2.15)
Duration of treatment <5years 220 (81.2) 51 (18.8) Ref Ref
≥5years 180 (73.8) 64 (26.2) 1.53 (1.01,2.33) 4.37 (2.11,9.02)***
Educational status No formal education 112 (84.8) 20 (15.2) Ref Ref
Primarily school 117 (78.0) 33 (22.0) 1.58 (0.86, 2.92) 0.59 (0.25, 1.44)
Secondary 88 (75.9) 28 (24.1) 1.78 (0.94,3.37) 0.91 (0.41,2.00)
Above 83 (70.9) 34 (29.1) 2.29 (1.23,4.27) 0.73 (0.34,1.59)
Admission history No 265 (86.0) 43 (14.0) Ref Ref
Yes 135 (65.2) 72 (34.8) 3.29 (2.14,5.06) 4.01 (1.99, 8.11)**
Physical illness Yes 25 (65.8) 13 (34.2) 1.91 (0.95,3.87) 1.79 (0.73,4.43)
No 375 (78.6) 102 (21.4) Ref Ref
Alcohol use disorder Dependent 151 (80.7) 36 (19.3) 1.33 (0.86,2.07) 1.12 (0.67,1.85)
Non-dependent 249 (75.9) 79 (24.1) Ref Ref
Family history of mental illness No 347 (80.0) 87 (20.0) Ref Ref
Yes 53 (65.4) 28 (34.6) 2.11 (1.26,3.53) 1.90 (1.04,3.48)*

Abbreviations: OR, Odds Ratio; CI, Confidence Interval. Ref: Reference category NB.*Persisted significant at P-value <0.05, ** significant at P-value ≤0.001. *** Significant at P-value <0.0001.