Table 2. Values at Each Time Point.
a Significant difference between surgery and no surgery groups (P-value <0.0001)
b No significant difference between surgery and no surgery groups (P-values of 1, 0.96, 0.74, and 0.36, respectively)
c Significant or nearly significant difference between surgery and no surgery groups (P-value=0.0141, 0.0585, 0.0013, and 0.023, respectively)
AA: Androgen ablation; RT: Radiotherapy; PSA: Prostate-specific antigen; CRP: C-reactive protein; WBC: White blood cells.
| Prior to AA | Prior to RT | Final Week of RT | 3 Months Post-RT | ||||||
| Labs | Prostatectomy History | n | Median (range) | n | Median (range) | n | Median (range) | n | Median (range) |
| PSA (ng/mL) | all | 68 | 9.1 (0-155.5)* | 187 | 1 (0.0-39.9)a | 49 | 0.0 (0.0-11.4)a | 190 | 0.1 (0.0-14.9)a |
| no | 54 | 10.0 (3.7-155.5) | 127 | 2.8 (0.0-39.9) | 23 | 1.5 (0.0-11.4) | 124 | 0.6 (0.0-14.9) | |
| yes | 14 | 0.6 (0.0-23.3) | 60 | 0.2 (0.0-3.1) | 26 | 0.0 (0.0-1.7) | 66 | 0.0 (0.0-3.3) | |
| CRP (μg/mL) | all | 46 | 1.4 (0.2-71.5)b | 172 | 2.6 (0.0-35.2)b | 177 | 2.2 (0.0-76.3)b | 176 | 2.3 (0.0-41.1)b |
| no | 39 | 1.5 (0.2-71.5) | 110 | 2.5 (0.0-30.6) | 113 | 2.2 (0.0-57.7) | 114 | 2.4 (0.0-41.1) | |
| yes | 7 | 1.2 (0.2-27.6) | 62 | 2.9 (0.0-35.2) | 64 | 2.1 (0.0-76.3) | 62 | 2.1 (0.0-15.2) | |
| WBC (103 cells/μL) | all | 83 | 6.9 (3.8-14.8)b | 200 | 6.5 (3-14.8)b | 191 | 4.7 (2.2-13.0)c | 190 | 5.0 (2.1-14.7)c |
| no | 66 | 6.7 (4.0-8.8) | 133 | 6.5 (3.0-14.8) | 123 | 4.9 (2.4-13.0) | 124 | 5.2 (2.1-14.7) | |
| yes | 17 | 7.0 (3.8-14.8) | 67 | 6.4 (4.0-11.0) | 68 | 4.6 (2.2-11.1) | 66 | 4.8 (2.2-8.1) | |
| Lymphocytes (103 cells/μL) | all | 79 | 1.7 (0.8-4.0)b | 198 | 1.9 (0.6-5.0)b | 191 | 0.67 (0.2-3.3)c | 187 | 0.9 (0.3-3.6)c |
| no | 62 | 1.8 (0.8-4.0) | 131 | 1.9 (0.6-5.0) | 123 | 0.7 (0.2-3.3) | 122 | 1.0 (0.3-3.6) | |
| yes | 17 | 1.6 (0.8-2.7) | 67 | 1.9 (0.8-4.9) | 68 | 0.6 (0.2-1.3) | 65 | 0.8 (0.3-1.9) | |