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. 2021 Nov 16;13(11):e19639. doi: 10.7759/cureus.19639

Table 4. The Effects of Androgen Ablation.

a Significant difference by androgen ablation

b Significant change through time

+ No significant difference by surgical status for CRP, WBC, or Lymphocytes

RT: Radiotherapy; PSA: Prostate-specific antigen; CRP: C-reactive protein; WBC: White blood cells; AA: Androgen ablation.

    With Androgen Ablation (n=106) Without Androgen Ablation (n=103)  
  Median (range) Median (range) p-value
pre-RT PSA (all) + 0.9 (0-30.2) 2.85 (0.0-39.9) 0.0072a
  no surgery 1.0 (0.0-30.2) 7.4 (0.4-39.9) <0.0001a
  surgery 0.0 (0.0-3.1) 0.2 (0.0-2.0) 0.7116
pre-RT CRP 2.35 (0-35.2) 2.85 (0.2-15.7) 0.7593
pre-RT WBC 6.3 (3-14.8) 6.55 (3.9-12.1) 0.5899
pre-RT Lymphocytes 1.82 (0.6-5.0) 1.94 (0.8-5.0) 0.3101
δpre-AA-->pre-RT PSA (all) + -7.2 (-125.3-1.1) N/A <0.0001b
  no surgery -8.1 (-125.3-1.1) <0.0001b
  surgery -0.75 (-20.7-0.1) 0.0156b
δpre-AA-->pre-RT CRP -0.05 (-66.1-21.5) 0.646
δpre-AA-->pre-RT WBC -0.1 (-5.8-4.4) 0.3598
δpre-AA-->pre-RT Lymphocytes 0.0 (-2.6-1.2) 0.9717