| 3.1 Depression symptoms ‐ short term |
8 |
750 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.83 [‐1.33, ‐0.32] |
| 3.2 Depression symptoms change score ‐ short term |
3 |
482 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.18 [‐0.36, ‐0.00] |
| 3.3 Depression remission ‐ short term |
4 |
646 |
Odds Ratio (IV, Random, 95% CI) |
2.06 [1.47, 2.89] |
| 3.4 Depression response ‐ short term |
5 |
891 |
Odds Ratio (IV, Random, 95% CI) |
2.73 [1.65, 4.54] |
| 3.5 All‐cause mortality ‐ short term |
2 |
437 |
Odds Ratio (IV, Random, 95% CI) |
0.38 [0.10, 1.47] |
| 3.6 All‐cause mortality ‐ long term |
2 |
661 |
Odds Ratio (IV, Random, 95% CI) |
0.89 [0.64, 1.25] |
| 3.7 Cardiovascular mortality ‐ long term |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
Totals not selected |
| 3.8 Myocardial infarction ‐ short term |
3 |
728 |
Odds Ratio (IV, Random, 95% CI) |
0.74 [0.26, 2.09] |
| 3.9 Myocardial infarction ‐ long term |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
Subtotals only |
| 3.10 Angina ‐ short term |
4 |
819 |
Odds Ratio (IV, Random, 95% CI) |
0.75 [0.44, 1.28] |
| 3.11 Heart failure ‐ short term |
3 |
602 |
Odds Ratio (IV, Random, 95% CI) |
0.93 [0.33, 2.62] |
| 3.12 Arrhythmia ‐ short term |
2 |
87 |
Odds Ratio (IV, Random, 95% CI) |
0.46 [0.01, 17.06] |
| 3.13 Stroke ‐ short term |
2 |
586 |
Odds Ratio (IV, Random, 95% CI) |
0.99 [0.20, 4.96] |
| 3.14 Coronary revascularisation procedure ‐ long term |
1 |
300 |
Odds Ratio (IV, Random, 95% CI) |
0.59 [0.32, 1.10] |
| 3.15 Healthcare costs ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.16 Hospitalisations ‐ short term |
3 |
514 |
Odds Ratio (M‐H, Random, 95% CI) |
0.58 [0.39, 0.85] |
| 3.17 Emergency department visits ‐ short term |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 3.18 Quality of life Q‐LES‐Q ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.19 Quality of life WHOQOL‐BREF Physical ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.20 Quality of life WHOQOL‐BREF Psychological ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.21 Quality of life WHOQOL‐BREF Social relationships ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.22 Quality of life WHOQOL‐BREF Environmental ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.23 Quality of life WHOQOL‐BREF Physical ‐ medium term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.24 Quality of life WHOQOL‐BREF Psychological ‐ medium term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.25 Quality of life WHOQOL‐BREF Social Relationships ‐ medium term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.26 Quality of life WHOQOL‐BREF Environmental ‐ medium term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.27 Systolic BP ‐ short term |
3 |
675 |
Mean Difference (IV, Random, 95% CI) |
‐0.24 [‐3.52, 3.05] |
| 3.28 Diastolic BP ‐ short term |
3 |
675 |
Mean Difference (IV, Random, 95% CI) |
0.60 [‐1.55, 2.74] |
| 3.29 Heart rate ‐ short term |
4 |
662 |
Mean Difference (IV, Random, 95% CI) |
‐0.80 [‐2.40, 0.79] |
| 3.30 Platelet biomarker βTG ‐ short term |
3 |
141 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.54 [‐0.99, ‐0.09] |
| 3.31 Platelet biomarker PF4 ‐ short term |
3 |
144 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.14 [‐0.48, 0.19] |
| 3.32 Platelet biomarker P‐selectin ‐ short term |
2 |
121 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.31 [‐1.12, 0.50] |
| 3.33 Platelet biomarker PECAM‐1 ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 3.34 Platelet biomarker TxB 2 ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 3.35 ECG PR interval ‐ short term |
3 |
635 |
Mean Difference (IV, Random, 95% CI) |
‐4.35 [‐8.40, ‐0.31] |
| 3.36 ECG QRS interval ‐ short term |
3 |
635 |
Mean Difference (IV, Random, 95% CI) |
2.37 [‐0.41, 5.15] |
| 3.37 ECG QT interval ‐ short term |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 3.38 ECG QTc interval ‐ short term |
3 |
635 |
Mean Difference (IV, Random, 95% CI) |
2.76 [‐1.96, 7.47] |
| 3.39 Non‐cardiac adverse events and side effects ‐ short term |
8 |
1193 |
Odds Ratio (M‐H, Random, 95% CI) |
1.44 [1.07, 1.92] |
