Li 2005.

Study characteristics
Methods	RCT design: parallel‐group trial Total N randomised: 87 Length of follow‐up: 6 weeks Analysis: unclear (2 cases dropped out in the intervention group, 3 cases dropped out in the control group)
Participants	Location: China Number of study centres and setting: hospitalised patients (number of centres unclear) CAD criteria: undergone CABG Depression criteria: self‐rated HAM‐D score > 18 Other entry criteria: unclear Exclusion criteria: unclear Treatment N: 43 (sex and age distribution unclear) Control N: 39 (sex and age distribution unclear) Comparability of groups: unclear
Interventions	Treatment: St John's wort extract (300 mg, 3 times a day) Control: placebo Duration of treatment: 6 weeks
Outcomes	Review outcomes: depression symptoms (HAM‐D score), depressive reductive rate (unclear from translation), pharmacological side effects Other outcomes: ventricular function (Tei‐Index)
Funding	Unclear
Notes	Comment: translated paper
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Comment: No sufficient information provided
Allocation concealment (selection bias)	Unclear risk	Comment: No sufficient information provided Quote from translation: "placebo‐control and blind evaluation"
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Comment: No sufficient information provided. HAMD was described as a self‐rated measure of depression Quote from translation: "placebo‐control and blind evaluation"
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Comment: No sufficient information provided
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Comment: No sufficient information provided
Selective reporting (reporting bias)	Unclear risk	Comment: No sufficient information provided
Other bias	Unclear risk	Comment: translated paper