Irfan 2020.

Study name	The effect of culturally adapted CBT‐based guided self help in depressed patients with myocardial infarction
Methods	RCT design: 2‐arm parallel‐group trial Total N randomised: 140 Length of follow‐up: 8 weeks Analysis: ITT with last‐observation‐carried‐forward
Participants	Location: Pakistan Number of study centres and setting: Punjab Institute of Cardiology, Lahore CAD criteria: myocardial infarction Depression criteria: score of 8 or more on HADS and fulfilling criteria of Major Depressive Disorder using DSM‐5 Other entry criteria: 18 to 65 years of age Exclusion criteria: patients using alcohol or drugs, significant cognitive impairment (intellectual disability or dementia), active psychosis, patients who have received CBT during the previous 12 months
Interventions	Intervention: culturally adapted cognitive‐behavioural therapy (CaCBT)‐based guided self‐help (using the book Khushi Aur Khatoon) Usual care: not specified Duration of treatment: 8 weeks
Outcomes	Change in HADS Depression Subscale score from baseline to end of therapy Change in World Health Organization Disability Assessment Schedule (WHODAS 2.0) score from baseline to end of therapy
Starting date	22 October 2019
Contact information	Muhammad Irfan, Professor of Psychiatry and Director Research, Peshawar Medical College Farooq Naeem, PhD, University of Toronto
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