Ma 2014.
Study name | The therapeutic effect of statins on patients with depression after acute coronary syndrome |
Methods | RCT design: 3‐arm parallel‐group trial Total N randomised: 180 Length of follow‐up: no follow‐up Analysis: not specified |
Participants | Location: China Number of study centres and setting: Tongji Hospital affiliated to Tongji University, Shanghai CAD criteria: diagnostic criteria of ACS based on guidelines, including ST elevation myocardial infarction, non‐ST elevation myocardial infarction, and unstable angina Depression criteria: based on PHQ, not further specified Other entry criteria: between 30 and 90 years of age Exclusion criteria: previous history of mental illness, suicidal tendencies, severe hepatic and renal dysfunction, anxiety state (HADS Anxiety score more than 7), left ventricular ejection fraction less than 0.45, haemodynamic instability, LDL‐c more than 3.37 mmol/L, allergic to statins or sertraline |
Interventions | Intervention 1: rosavastatin calcium 20 mg/d Intervention 2: sertraline 25 to 50 mg/d Intervention 3: rosavastatin calcium 5 mg/d Duration of treatment: not specified |
Outcomes | Not specified |
Starting date | 14 December 2014 |
Contact information | Wenlin Ma
NO.389 Xincun Rd, Putuo district, Shanghai, China T: +86 18621892703 E: mawenlin@medmail.com.cn |
Notes |