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. 2021 Dec 1;12:782831. doi: 10.3389/fimmu.2021.782831

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Copyright © 2021 Fernandes, Costa, Scomparin, Freire, Guimarães and Campos

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distinct behavioral response to CUS of outbred WT and iNOS K.O. mice. (A) total distance traveled on the open field test (n=5/group); latency for the first immobility episode (B) and total immobility time on the tail suspension test (n=4,4,5 and 4, respectively) (C); (D) latency to feed in a novel environment (E): total feeding consumption during five minutes in home-cage (n=5/group). Data presented as mean ± S.E.M. *p < 0,05 from WT non-stressed; # indicates p < 0.05 on genotype factor.