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. 2021 Dec 1;12:793523. doi: 10.3389/fgene.2021.793523

TABLE 6.

SNPs in 3′UTR in target gene of miRNA involved in various disease.

S. No Gene miRNA SNP reported Disease Reference
1 APOC3 miR-4271 rs4225 Coronary heart disease Moszyńska et al. (2017)
G>T
2 APOA5 miR-485-5p rs2266788 G>A Hyper-triglyceridemia Moszyńska et al. (2017)
3 PLIN4 miR-522 rs8887 Antropometrics (Obesity related) Moszyńska et al. (2017)
T>C,G
4 FXN miR-124-3p rs1145043 Friedrich’s atria FRDA Moszyńska et al. (2017)
G>T
5 SNCA miR-34b rs10024743 Parkinson’s disease Moszyńska et al. (2017)
T>G
6 EFNB2 miR-137 rs550067317 Schizophrenia Moszyńska et al. (2017)
A>C
7 FGF20 miR-433 rs12720208 Parkinson’s disease Cao et al. (2016); Moszyńska et al. (2017)
C/T
8 AGTR1 miR-155 rs5186 Hypertension Jin et al. (2008); Cao et al. (2016); Moszyńska et al. (2017)
A>C Renal disease
9 DHFR miR-24 rs34764978 C>T Methotrexate resistance Moszyńska et al. (2017)
10 HLA-G miR-48a rs1063320 C>G Childhood asthma Moszyńska et al. (2017)
miR-152
11 HTR1B miR-96 rs13212041 A/G Arson/property damage Moszyńska et al. (2017)
12 HTR3E miR-510 rs56109847 G>A Diarrhea irritable bowel syndrome Moszyńska et al. (2017)
13 TGFB1 miR-187 rs1982073 (rs1800470) Frozen shoulder development Wynendaele et al. (2010); Hoss et al. (2014)
G>A,C
14 MMP9 miR-491-5p rs1056628 SLE, Early neurologic deterioration Wynendaele et al. (2010); Sondermeijer et al. (2011)
A>C
15 HTR3E miR-510 rs62625044 Irritable bowel syndrome Usiello et al. (2000); Cao et al. (2016)
G>A rs56109847
16 PFAS miR-149-3p rs1132554 Alcohol related neurodevelopment disorder Cao et al. (2016)
C>T
17 TRIB2 miR-877-5p rs1057001 Obesity Olefsky (2001); Cao et al. (2016)
T>A
18 TMCO1 miR-296-3p rs6660601 Skeletal anomalies, mental retardation syndrome Cao et al. (2016)
C>T
19 SRSF3 miR-7f-2-3p rs7344 POAG- primary open angle glaucoma Crocco et al. (2015); Cao et al. (2016)
T>C
20 CAV2 miR-244-5p rs1052990 POAG Cao et al. (2016)
T>C,G
21 AAGAB miR-329-5p rs1050285 Punctuate palmoplantar keratoderma type1 Cao et al. (2016)
T>C
22 ABO miR-855-3p rs8176751 Hematological phenotype Cao et al. (2016)
C>A,T
23 MTPN Let-7/miR-98 rs17168525 Cardiac hypertrophy Jin et al. (2008); Wang et al. (2013a)
G>A
24 MS4A6A miR-382-3p rs610932 LOAD- Late onset Alzheimer disease Bäckman et al. (2006); Erturk et al. (2014)
T>G
25 TCF-21 miR-224-5p rs12190287 C>G,T Acute Coronary syndrome Noble (2003); Erturk et al. (2014)
26 POCRID miR-425-3p rs7097 DLBCL Abo-Elmatty and Mehanna (2019)
miR-5444a/miR-507 C>T Diffuse large B-cell lymphoma
27 PRKD3 miR-329-3p rs8243 Polycystic kidney and liver disease Abo-Elmatty and Mehanna (2019)
mir495-3p C>A
28 ZNF155 miR-708-5p rs442220 Herpes simplex virus 1 Abo-Elmatty and Mehanna (2019)
miR-28-5p G>A,C