Table 7.
Comparison results with literature.
| Predicted Epitopes in [17] |
4V |
5V |
6V |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Epitope | Len | Ant | Det | Len | Ant | Det | Len | Ant | Det | Len | Ant |
| FHAIHVSGTNG | 11 | 0.8882 | ✓ | 18 | 0.6317 | ✓ | 18 | 0.6317 | ✓ | 18 | 0.6317 |
| TLDSKTQSLLIVNNATNV | 18 | 0.7295 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| PGDSSSGWTAGA | 12 | 0.0820 | ✓ | 17 | 0.2386 | ✓ | 17 | 0.2386 | ✓ | 18 | 0.5144 |
| NENGTITDA | 9 | 0.5257 | ✓ | 9 | 0.5257 | ✓ | 10 | 0.6020 | ✓ | 11 | 0.7882 |
| IYQTSNFRV | 9 | 0.3109 | ✓ | 11 | 0.2839 | ✓ | 11 | 0.2839 | ✓ | 16 | 0.8559 |
| IAWNSNNLDSK | 11 | 1.2444 | ✓ | 11 | 1.2444 | ✓ | 12 | 0.9178 | ✓ | 13 | 0.7773 |
| STEIYQAGSTPCNGV | 15 | −0.0513 | ✓ | 16 | 0.0539 | ✓ | 18 | −0.0751 | ✓ | 19 | −0.0745 |
| RVYSTGSNVFQTRA | 14 | 0.3248 | ✓ | 14 | 0.3248 | ✓ | 14 | 0.3248 | ✓ | 18 | 0.5620 |
| GAEHVNNSYE | 10 | 0.8739 | ✓ | 10 | 0.8739 | ✓ | 10 | 0.8739 | ✓ | 10 | 0.8739 |
| YICGDSTECSNLLLQ | 15 | −0.0093 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| GSFCTQLNRALTG | 13 | 0.4763 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| AVEQDKNTQE | 10 | 0.2792 | ✓ | 12 | 0.5008 | ✓ | 12 | 0.5008 | ✗ | – | – |
| DEMIAQYTSALLAG | 14 | 0.1366 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| LQSLQTYVT | 9 | −0.0592 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| RASANLAATKMSECVLGQ | 18 | 0.4001 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| TDNTFVSGNCD | 11 | 0.0820 | ✓ | 14 | 0.1793 | ✓ | 14 | 0.1793 | ✓ | 14 | 0.1793 |
| KNHTSPDV | 8 | 0.9006 | ✓ | 8 | 0.9006 | ✓ | 8 | 0.9006 | ✓ | 8 | 0.9006 |
| GINASVVNIQ | 10 | 1.0425 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| EVAKNLNESL | 10 | −0.0432 | ✓ | 10 | −0.0432 | ✓ | 14 | 0.1512 | ✗ | – | – |
| Average | 0.4514 | 0.4762 | 0.4608 | 0.6009 | |||||||
| Predicted Epitopes in [39] | 4V | 5V | 6V | ||||||||
| EVRQIAPGQTGKIADY | 16 | 1.3837 | ✓ | 16 | 1.3837 | ✓ | 17 | 1.0936 | ✓ | 19 | 1.1515 |
| TVEKGIYQTSNFRVQP | 16 | 0.6733 | ✓ | 16 | 0.6733 | ✓ | 16 | 0.6733 | ✗ | – | – |
| HRSYLTPGDSSSGWTA | 16 | 0.6017 | ✓ | 16 | 0.6017 | ✓ | 17 | 0.4892 | ✓ | 17 | 0.4892 |
| YVGYLQPRTFLLKYNE | 16 | 0.5108 | ✓ | 18 | 0.4816 | ✓ | 18 | 0.4816 | ✓ | 18 | 0.4816 |
| CGPKKSTNLVKNKCVN | 16 | 0.2006 | ✓ | 20 | 0.8935 | ✓ | 20 | 0.8935 | ✗ | – | – |
| TKTSVDCTMYICGDST | 16 | 0.0937 | ✓ | 18 | 0.1426 | ✓ | 18 | 0.1426 | ✗ | – | – |
| TEIYQAGSTPCNGVEG | 16 | −0.0105 | ✓ | 16 | −0.0105 | ✓ | 16 | −0.0105 | ✓ | 18 | 0.0583 |
| FERDISTEIYQAGSTP | 16 | −0.2904 | ✓ | 17 | −0.1383 | ✓ | 17 | −0.1383 | ✓ | 19 | −0.0782 |
| FAMQMAYRFNGIGVTQ | 16 | 1.3096 | ✓ | 18 | 1.4137 | ✗ | – | – | ✗ | – | – |
| IGKIQDSLSSTASALG | 16 | 0.654 | ✓ | 19 | 0.5712 | ✓ | 19 | 0.5712 | ✓ | 20 | 0.4992 |
| LQSYGFQPTNGVGYQP | 16 | 0.5258 | ✓ | 17 | 0.4203 | ✓ | 17 | 0.4203 | ✗ | – | – |
| SWMESEFRVYSSANNC | 16 | 0.1724 | ✓ | 16 | 0.1724 | ✓ | 16 | 0.1724 | ✓ | 16 | 0.1724 |
| TRFQTLLALHRSYLTP | 16 | 0.5115 | ✓ | 18 | 0.5595 | ✗ | – | – | ✗ | – | – |
| PQIITTDNTFVSGNCD | 16 | 0.2404 | ✓ | 16 | 0.2404 | ✓ | 16 | 0.2404 | ✓ | 16 | 0.2404 |
| QKEIDRLNEVAKNLNE | 16 | 0.0684 | ✓ | 18 | 0.1255 | ✓ | 18 | 0.1255 | ✗ | – | – |
| KQIYKTPPIKDFGGFN | 16 | −0.2241 | ✓ | 16 | −0.2241 | ✓ | 16 | −0.2241 | ✓ | 16 | −0.2241 |
| SKRVDFCGK | 9 | 1.7321 | ✓ | 9 | 1.7321 | ✓ | 12 | 1.3607 | ✓ | 12 | 1.3607 |
| GKYEQY | 6 | 1.2821 | ✓ | 6 | 1.2821 | ✓ | 6 | 1.2821 | ✓ | 6 | 1.2821 |
| LDSKVGGNYNYLY | 13 | 0.8331 | ✓ | 14 | 0.8329 | ✓ | 14 | 0.8329 | ✓ | 14 | 0.8329 |
| TPGDSSSGWTAGA | 13 | 0.1212 | ✓ | 18 | 0.5144 | ✓ | 18 | 0.5144 | ✓ | 18 | 0.5144 |
| FLPFQ | 5 | NA | ✓ | 8 | 1.4427 | ✓ | 8 | 1.4427 | ✓ | 9 | 1.1432 |
| TSNFRVQPTE | 10 | 1.3571 | ✓ | 11 | 1.2323 | ✓ | 11 | 1.2323 | ✓ | 11 | 1.2323 |
| TNLCPF | 6 | 1.2508 | ✓ | 8 | 0.8906 | ✓ | 13 | 1.04 | ✗ | – | – |
| DPSKPSKRSF | 10 | 0.8148 | ✓ | 10 | 0.8148 | ✓ | 10 | 0.8148 | ✓ | 11 | 0.6286 |
| EVFNATRFASVYAWNRKRI | 19 | 0.2655 | ✓ | 19 | 0.2655 | ✗ | – | – | ✗ | – | – |
| AEVQIDR | 7 | −0.4355 | ✓ | 8 | −0.2814 | ✓ | 11 | −0.0004 | ✓ | 11 | −0.0004 |
| PTNGVG | 6 | −1.1441 | ✓ | 7 | −0.7278 | ✓ | 8 | −0.3112 | ✓ | 8 | −0.3112 |
| QLTPTWRVYSTGSNVFQTRA | 20 | 0.7725 | ✓ | 20 | 0.7725 | ✓ | 20 | 0.7725 | ✗ | – | – |
| TMSLGAENSVAYSNNS | 16 | 0.6687 | ✓ | 16 | 0.6687 | ✓ | 16 | 0.6687 | ✓ | 16 | 0.6687 |
| GFNCYFPLQSY | 11 | 0.9224 | ✓ | 18 | 0.8567 | ✓ | 18 | 0.8567 | ✓ | 18 | 0.8567 |
| EPQIITTDNT | 10 | 0.7545 | ✓ | 13 | 0.6684 | ✓ | 16 | 0.5227 | ✓ | 17 | 0.3342 |
| NSYECDIPIG | 10 | 0.6533 | ✓ | 11 | 0.8366 | ✓ | 11 | 0.8366 | ✓ | 14 | 0.9296 |
| IYKTPPIKDFGGFNF | 15 | 0.0696 | ✓ | 15 | 0.0696 | ✓ | 15 | 0.0696 | ✓ | 15 | 0.0696 |
| Average | 0.5106 | 0.5763 | 0.6114 | 0.5362 | |||||||
| Predicted Epitopes in [44] | 4V | 5V | 6V | ||||||||
| LTPGDSSSGWTAG | 13 | 0.4950 | ✓ | 18 | 0.3768 | ✓ | 18 | 0.3768 | ✓ | 18 | 0.3768 |
| VRQIAPGQTGKIAD | 14 | 1.2606 | ✓ | 15 | 1.3487 | ✓ | 16 | 1.0388 | ✓ | 19 | 1.1515 |
| YQAGSTPCNGV | 11 | 0.0881 | ✓ | 13 | 0.1909 | ✓ | 15 | 0.2479 | ✓ | 15 | 0.2479 |
| ILPDPSKPSKRS | 12 | 0.5322 | ✓ | 12 | 0.5322 | ✓ | 12 | 0.5322 | ✓ | 12 | 0.5322 |
| Average | 0.594 | 0.6121 | 0.5489 | 0.5771 | |||||||
| Predicted Epitopes in [43] | 4V | 5V | 6V | ||||||||
| DVVNQNAQALNTLVKQL | 17 | 0.0320 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| EAEVQIDRLITGRLQSL | 17 | −0.1784 | ✓ | 20 | −0.0881 | ✗ | – | – | ✗ | – | – |
| GAGICASY | 8 | 0.5210 | ✓ | 13 | 0.6871 | ✓ | 13 | 0.6871 | ✓ | 17 | 0.4587 |
| GSFCTQLN | 8 | 0.8144 | ✓ | 9 | 0.9306 | ✓ | 9 | 0.9306 | ✗ | – | – |
| KGIYQTSN | 8 | 0.2441 | ✓ | 8 | 0.2441 | ✓ | 9 | 0.4627 | ✓ | 10 | 0.3992 |
| AMQMAYRF | 8 | 0.9776 | ✓ | 9 | 1.0278 | ✓ | 11 | 1.2909 | ✓ | 11 | 1.2909 |
| KNHTSPDVDLGDISGIN | 17 | 1.1116 | ✓ | 18 | 1.0631 | ✓ | 19 | 0.8800 | ✓ | 19 | 0.8800 |
| AATKMSECVLGQSKRVD | 17 | 0.6159 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| PFAMQMAYRFNGIGVTQ | 17 | 1.3306 | ✓ | 18 | 1.4137 | ✗ | – | – | ✗ | – | – |
| QALNTLVKQLSSNFGAI | 17 | 0.0872 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| QLIRAAEIRASANLAAT | 17 | 0.3714 | ✓ | 19 | 0.3381 | ✗ | – | – | ✗ | – | – |
| QQFGRD | 6 | −0.5500 | ✓ | 6 | −0.5500 | ✓ | 6 | −0.5500 | ✓ | 6 | −0.5500 |
| RASANLAATKMSECVLG | 17 | 0.4414 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| RLITGRLQSLQTYVTQQ | 17 | −0.2774 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| SLQTYVTQQLIRAAEIR | 17 | −0.0120 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| Average | 0.5158 | 0.5629 | 0.6169 | 0.4958 | |||||||
| Predicted Epitopes in [33] | 4V | 5V | 6V | ||||||||
| DPFLGVYYHKNNKSWME | 17 | 0.5821 | ✓ | 17 | 0.5821 | ✓ | 17 | 0.5821 | ✓ | 17 | 0.5821 |
| MDLEGKQGNFKNL | 13 | 1.2592 | ✓ | 13 | 1.2592 | ✓ | 13 | 1.2592 | ✗ | – | – |
| KHTPINLVRDLPQGFS | 16 | 0.6403 | ✓ | 17 | 0.5695 | ✓ | 17 | 0.5695 | ✗ | – | – |
| TPGDSSSGWTA | 11 | 0.2473 | ✓ | 12 | 0.0746 | ✓ | 17 | 0.4892 | ✓ | 17 | 0.4892 |
| KSFTVEKGIYQTSNFRVQP | 19 | 0.5729 | ✓ | 19 | 0.5729 | ✓ | 19 | 0.5729 | ✗ | – | – |
| SNKKFLPF | 8 | 1.3952 | ✓ | 8 | 1.3952 | ✓ | 8 | 1.3952 | ✓ | 9 | 1.1432 |
| TNTSN | 5 | NA | ✓ | 5 | ✓ | 5 | ✓ | 5 | |||
| NCTEVPVAIHADQLTPT | 17 | 0.3987 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| RVYSTGSNVFQ | 11 | −0.1000 | ✓ | 13 | 0.3359 | ✓ | 13 | 0.3359 | ✗ | – | – |
| VNNSYECDIPI | 11 | 0.6124 | ✓ | 16 | 0.9123 | ✓ | 16 | 0.9123 | ✗ | – | – |
| YTMSLGAENSVAYSNN | 16 | 0.6434 | ✓ | 16 | 0.6434 | ✓ | 16 | 0.6434 | ✓ | 16 | 0.6434 |
| EQDKNTQ | 7 | 0.1017 | ✓ | 7 | 0.1017 | ✓ | 7 | 0.1017 | ✓ | 7 | 0.1017 |
| KQIYKTPPIKDFGGF | 15 | −0.3896 | ✓ | 15 | −0.3896 | ✓ | 15 | −0.3896 | ✓ | 15 | −0.3896 |
| PDPSKPSK | 8 | 0.0621 | ✓ | 8 | 0.0621 | ✓ | 8 | 0.0621 | ✓ | 8 | 0.0621 |
| LADAGFIKQYGDCLG | 15 | 0.2071 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| EAEVQ | 5 | NA | ✓ | 5 | NA | ✓ | 5 | NA | ✓ | 11 | −0.0004 |
| GQSKRVDFC | 9 | 1.7790 | ✓ | 11 | 1.4088 | ✓ | 12 | 1.3607 | ✓ | 12 | 1.3607 |
| RNFYEPQIITTD | 12 | 0.3529 | ✓ | 15 | 0.6381 | ✓ | 16 | 0.6504 | ✓ | 20 | 0.2624 |
| Average | 0.5228 | 0.5833 | 0.6103 | 0.4255 | |||||||
| Predicted Epitopes in [47] | 4V | 5V | 6V | ||||||||
| RGVYYPDK | 8 | 1.0191 | ✓ | 8 | 1.0191 | ✓ | 8 | 1.0191 | ✓ | 11 | 0.5200 |
| RSSVLHST | 8 | 0.5459 | ✓ | 10 | 0.5404 | ✓ | 10 | 0.5404 | ✗ | – | – |
| DLFLPFFS | 8 | −0.3099 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| FHAIHV | 6 | 1.6766 | ✓ | 18 | 0.6317 | ✓ | 18 | 0.6317 | ✓ | 18 | 0.6317 |
| NPVLPFN | 7 | 0.5863 | ✓ | 9 | 0.0146 | ✓ | 9 | 0.0146 | ✓ | 9 | 0.0146 |
| QSLLIVN | 7 | 0.8168 | ✓ | 15 | 0.5156 | ✓ | 15 | 0.5156 | ✗ | – | – |
| NVVIKVCEFQ | 10 | −0.1498 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| CNDPFLGVYYH | 11 | 0.4109 | ✓ | 17 | 0.5314 | ✓ | 17 | 0.5314 | ✓ | 17 | 0.5314 |
| FEYVSQP | 7 | 0.9073 | ✓ | 11 | 0.1016 | ✓ | 11 | 0.1016 | ✗ | – | – |
| INLVRDL | 7 | −0.3198 | ✓ | 14 | 0.4022 | ✓ | 14 | 0.4022 | ✓ | 17 | 0.4924 |
| LEPLVDLP | 8 | −0.3271 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| QTLLALHRSY | 10 | 0.5596 | ✓ | 17 | 0.5921 | ✗ | – | – | ✗ | – | – |
| AAYYVGYL | 8 | 0.5218 | ✓ | 12 | 0.9255 | ✗ | – | – | ✗ | – | – |
| PRTFLLK | 7 | −1.3917 | ✓ | 10 | −0.2800 | ✓ | 10 | −0.2800 | ✓ | 12 | −0.2227 |
| AVDCALDP | 8 | 0.7730 | ✓ | 16 | 0.5804 | ✓ | 16 | 0.5804 | ✓ | 16 | 0.5804 |
| TNLCPFG | 7 | 1.1812 | ✓ | 8 | 0.8906 | ✓ | 13 | 1.0400 | ✗ | – | – |
| SNCVADYSVLYNS | 13 | −0.1828 | ✓ | 13 | 0.0152 | ✗ | – | – | ✗ | – | – |
| TFKCYGVSPT | 10 | 1.5059 | ✓ | 20 | 0.8913 | ✓ | 20 | 0.8913 | ✗ | – | – |
| TGCVIA | 6 | 0.4716 | ✓ | 10 | 0.0996 | ✓ | 13 | −0.1592 | ✓ | 14 | −0.1234 |
| CYFPLQSY | 8 | 0.9394 | ✓ | 8 | 0.9394 | ✓ | 12 | 0.8719 | ✓ | 12 | 0.8719 |
| FGGVSVIT | 8 | 0.7715 | ✓ | 12 | 0.4578 | ✓ | 13 | 0.4931 | ✓ | 13 | 0.4931 |
| CTEVPVAIHAD | 11 | 0.0499 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| AGCLIGA | 7 | 0.1743 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| GAGICASY | 8 | 0.5210 | ✓ | 13 | 0.6871 | ✓ | 13 | 0.6871 | ✓ | 17 | 0.4587 |
| VASQSII | 7 | −0.0188 | ✓ | 16 | 0.3257 | ✓ | 16 | 0.3257 | ✓ | 18 | 0.4018 |
| TTEILPVS | 8 | 1.2071 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| SVDCTMY | 7 | 1.0932 | ✓ | 17 | −0.0258 | ✓ | 18 | 0.1426 | ✗ | – | – |
| SNLLLQYGSFCTQL | 14 | 0.7599 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| VFAQVKQI | 8 | 0.5854 | ✓ | 14 | 0.3493 | ✓ | 15 | 0.4451 | ✗ | – | – |
| SQILPD | 6 | −0.1542 | ✓ | 8 | 0.0383 | ✓ | 8 | 0.0383 | ✓ | 11 | 0.5569 |
| YGDCLGD | 7 | −0.5555 | ✓ | 12 | 0.5494 | ✓ | 14 | 0.0416 | ✗ | – | – |
| RDLICAQ | 7 | 1.1443 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| LTVLPPL | 7 | 0.6786 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| YTSALLAG | 8 | 0.3798 | ✓ | 20 | 0.3640 | ✗ | – | – | ✗ | – | – |
| LNTLVKQL | 8 | −0.7591 | ✓ | 16 | −0.0646 | ✓ | 16 | −0.0646 | ✗ | – | – |
| ISSVLND | 7 | 0.0414 | ✓ | 11 | 0.7339 | ✓ | 12 | 0.6035 | ✗ | – | – |
| SLQTYVTQQ | 9 | −0.0089 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| SECVLGQS | 8 | −0.0110 | ✓ | 13 | 0.5417 | ✗ | – | – | ✗ | – | – |
| PHGVVFLHVTYVPA | 14 | 0.8058 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| PAICHDG | 7 | −1.0100 | ✓ | 15 | 0.2145 | ✓ | 15 | 0.2145 | ✗ | – | – |
| SGNCDVVIGI | 10 | 0.7421 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| ASVVNI | 6 | 0.8671 | ✓ | 13 | 0.1922 | ✗ | – | – | ✗ | – | – |
| Average | 0.3938 | 0.4258 | 0.4011 | 0.4005 | |||||||
| Predicted Epitopes in [45] | 4V | 5V | 6V | ||||||||
| VRQIAPGQTGKIAD | 14 | 1.2606 | ✓ | 15 | 1.3487 | ✓ | 16 | 1.0388 | ✓ | 19 | 1.1515 |
| VLGQSKRVDFCGKG | 14 | 1.3582 | ✗ | – | – | ✗ | – | – | ✗ | – | – |
| GLTGTGVLTESNKK | 14 | 1.0227 | ✓ | 14 | 1.0227 | ✓ | 14 | 1.0227 | ✓ | 16 | 0.6686 |
| KIADYNYKLPDDFT | 14 | 0.9567 | ✓ | 14 | 0.9567 | ✓ | 14 | 0.9567 | ✓ | 14 | 0.9567 |
| Average | 1.1495 | 1.1094 | 1.006 | 0.9256 | |||||||
| Predicted Epitopes in [46] | 4V | 5V | 6V | ||||||||
| DPFLGVYYHKNNKSWME | 17 | 0.5821 | ✓ | 17 | 0.5821 | ✓ | 17 | 0.5821 | ✓ | 17 | 0.5821 |
| MDLEGKQGNFKNL | 13 | 1.2592 | ✓ | 13 | 1.2592 | ✓ | 13 | 1.2592 | ✗ | – | – |
| KHTPINLVRDLPQGFS | 16 | 0.6403 | ✓ | 17 | 0.5695 | ✓ | 17 | 0.5695 | ✗ | – | – |
| TPGDSSSGWTA | 11 | 0.2473 | ✓ | 12 | 0.0746 | ✓ | 17 | 0.4892 | ✓ | 17 | 0.4892 |
| KSFTVEKGIYQTSNFRVQP | 19 | 0.5729 | ✓ | 19 | 0.5729 | ✓ | 19 | 0.5729 | ✗ | – | – |
| VNNSYECDIPI | 11 | 0.6124 | ✓ | 16 | 0.9123 | ✓ | 16 | 0.9123 | ✗ | – | – |
| YTMSLGAENSVAYSNN | 16 | 0.6434 | ✓ | 16 | 0.6434 | ✓ | 16 | 0.6434 | ✓ | 16 | 0.6434 |
| Average | 0.6111 | 0.6591 | 0.7184 | 0.5716 | |||||||