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. 2021 Dec 9;27(12):2224–2233. doi: 10.1038/s41591-021-01573-6

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© The Author(s) 2021, corrected publication 2022

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Fig. 1 — The study protocol planned to enroll 8 participants per treatment group. Six of 8 participants were allocated in the 0.6 mg kg⁻¹ dose group due to the decision to augment the premedication regimen with steroid to assess its potential mitigation of infusion-related reactions (0.6 mg kg⁻¹ + steroid group). ^aParticipants received loratadine and ranitidine 90 min before infusion. ^bParticipants received loratadine, ranitidine (sentinel, expansion) and acetaminophen (expansion) 90 min before infusion. ^cParticipants received steroid (dexamethasone) and diphenhydramine and famotidine 90 min before infusion. ^dParticipants received diphenhydramine and famotidine 90 min before infusion. ^eParticipants were administered two 0.3 mg kg⁻¹ doses on days 1 and 8.