Table 2.

Parameter estimates from hierarchical linear regression models of diagnostic status, PSMD, and their interaction product as predictors of cognitive performance.

	PSMD (10−4 mm2/s)			Group (LLD vs. controls)			PSMD × Group
Cognitive measure	Estimate (df)	SE	p-Value	Estimate	SE	p-Value	Estimate	SE	t-Value	p-Value
HVLT Immediate	−0.45 (104)	1.37	0.746	−0.69	0.19	<0.001	−1.45	2.32	−0.63	0.532
HVLT Delayed	−1.64 (105)	1.36	0.232	−0.65	0.19	0.001	−5.87	2.23	−2.6	0.010
Trail Making Test, Part A	5.34 (105)	1.36	<0.001	0.27	0.19	0.157	5.17	2.26	2.29	0.024
Trails B-A	0.15 (97)	1.47	0.918	0.60	0.21	0.005	1.4	2.53	0.553	0.582
Stroop Interference	−2.38 (108)	1.44	0.112	0.29	0.21	0.167	−5.9	2.47	−2.39	0.019
Animal Naming	−3.85 (106)	1.39	0.007	−0.39	0.19	0.047	−4.7	2.31	−2.03	0.046

SE standard error, HVLT Hopkins Verbal Learning Test, PSMD peak width of skeletonized mean diffusivity, LLD late-life depression.