Table 1.
Patient demographics | |
Total number of patients | 39 |
Age (years, mean, range) | 55.2 (29-80) |
Men | 26 (66.7) |
Primary kidney disease | |
Diabetes | 11 |
Vascular Disease | 3 |
Glomerulonephritis | 8 |
ADPKD | 4 |
Unknown | 5 |
Other | 8 |
Davies Comorbidity Score (%) | |
0 | 14 (36) |
1 | 14 (36) |
2 | 7 (18) |
3 | 3 (7.7) |
4 | 0 |
5 | 1 (2.6) |
Dialysis vintage, months median (IQR) | 16.1 (6-31.3) |
Weekly total (renal+peritoneal) Kt/V median (IQR) | 1.94 (1.78-2.35) |
GFR* (mL/min) median (IQR) | 1.95 (0.76-6.01) |
Blood Group AB0 (%) | |
0 | 19 (48.7) |
A | 12 (30.8) |
B | 6 (15.4) |
AB | 2 (5.1) |
Laboratory (mean ± SD) | |
Hemoglobin (g/dL) | 10.6 ± 1.39 |
Leukocytes (G/L) | 7.2 ± 2.11 |
Thrombocytes (G/L) | 225 ± 75.34 |
Albumin (g/L) | 3.6 ± 3.45 |
Sodium (mmol/L) | 136 ± 3.23 |
Potassium (mmol/L) | 4.4 ± 0.63 |
Calcium (mmol/L) | 2.25 ± 0.18 |
Phosphate (mmol/L) | 1.77 ± 0.42 |
Bicarbonate (mmol/L) | 25.8 ± 3.25 |
C-reactive protein (mg/dL) | 0.52 ± 0.69 |
Body mass index (kg/m2) | 27 ± 5.37 |
Obesity (BMI > 30 kg/m2) (%) | 10 (25.6) |
Medication (n) | |
Immunosuppressive therapy | 7 |
RAAS-inhibitor medication | 20 |
Vitamin D medication | 32 |
Antibody titer (U/mL) median (IQR) | |
after 1st dose | 6.62 (1.57-22.5) |
after 2nd dose | 968 (422.5-2500) |
Data are presented as n (%), mean ± SD or as median (IQR); Other = Alport syndrome (1), GVHD-associated TMA (1), cardiorenal syndrome (1), secondary FSGS (1), AL-Amyloidosis (1), glomerulosclerosis (1), nephronophtisis (1), scleroderma (1): GVHD, graft versus host disease; TMA, thrombotic microangiopathy; FSGS, focal segmental glomerulosclerosis; BMI, body mass index; weekly Kt/V, clearance of urea x time/volume; GFR, residual glomerular filtration rate; RAAS, renin-angiotensin-aldosteron system; CNI, calcineurin inhibitors; MMF, mycophenolate-mofetil. *residual GFR was calculated as mean of renal creatinine and renal urea clearance using 24 h urine samples.